Issues in Opioid Therapy for the Treatment of Cancer Pain

  • K. M. Foley
Part of the Developments in Critical Care Medicine and Anesthesiology book series (DCCA, volume 29)


Evaluation and treatment of pain in the patient with cancer has now evolved to encompass a series of clinical guidelines which define a comprehensive approach to the management of this difficult medical problem. Current knowledge in cancer pain includes the description of the common cancer pain syndromes in this population, as well as their postulated neurophysiologic mechanisms; a classification of the types of patients with pain, the different types of pain (acute, chronic, breakthrough) and the psychological factors that contribute to and alter the pain complaint; the development and implementation of well-validated pain measurement methodologies to assess pain intensity, degree of relief, and mood (psychological distress); the modeling of pharmacokinetic pharmacodynamic relationships to correlate opioid drug distribution with pain relief and side-effects; and refined use of anesthetic and neurosurgical approaches and the broader integration of cognitive-behavioral approaches (1–16).


Neuropathic Pain Cancer Pain Opioid Drug Cancer Pain Management Chronic Cancer Pain 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer Science+Business Media Dordrecht 1994

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  • K. M. Foley

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