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The Textbook of Peritoneal Dialysis pp 115–134Cite as

Peritoneal lymphatics

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Abstract

The peritoneal lymphatics serve as a route for continuous absorption of fluids and solutes from the peritoneal cavity by convective flow [1, 2]. The important role of lymphatic drainage from the peritoneal cavity in the pathogenesis of ascites due to liver disease or malignancy is well established [3–16] and the considerable absorptive capacity of the peritoneal lymphatics has been utilized to perform intraperitoneal blood transfusions in the fetus and in children [19–21]. However, until recently, kinetic studies of peritoneal dialysis iatrogenic “ascites” have tended to focus only on fluid and solute exchange between the peritoneal microcirculation and the instilled dialysis solution and have neglected the role of the peritoneal lymphatics [22–39]. The efficiency of peritoneal dialysis is assessed by measuring solute clearances and net ultrafiltration volumes. These indices of dialysis efficacy represent the cumulative balance of transperitoneal transport into and out of the peritoneal cavity and therefore incorporate the role of backfiltration from the peritoneal cavity. Absorption from the peritoneal cavity can occur by two mechanisms; uptake via the peritoneal cavity lymphatics (translymphatic absorption) or uptake by the peritoneal capillaries (transcapillary absorption).

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Authors
  1. Robert A. Mactier
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  2. Ramesh Khanna
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Editors and Affiliations

  1. Department of Renal Medicine, Manchester Royal Infirmary, Manchester, UK

    Ram Gokal

  2. Division of Nephrology, Department of Internal Medicine, School of Medicine, University of Missouri, Health Sciences Center and Dalton Cardiovascular Research Center, Columbia, Missouri, USA

    Karl D. Nolph

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Mactier, R.A., Khanna, R. (1994). Peritoneal lymphatics. In: Gokal, R., Nolph, K.D. (eds) The Textbook of Peritoneal Dialysis. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0814-0_5

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  • DOI: https://doi.org/10.1007/978-94-011-0814-0_5

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