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Ultrastructure and pathology of the peritoneum in peritoneal dialysis

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Book cover The Textbook of Peritoneal Dialysis

Abstract

Following the first histological description by Von Recklinghausen in 1863 of the endothelioid covering of the peritoneum [1], the limited resolution of the light microscope prevented any deeper probing of the structure of the thin cellular monolayer we now call the mesothelium. Thus it is not surprising that little interest was shown in the barely visible lining of the peritoneum until the inception of CAPD in the late 1970s stimulated a natural curiosity in the morphological determinants of peritoneal dialysis and a concern over the possible pathological consequences of continual immersion in dialysate. It was therefore as recent as 1981 before the first electron micrographs of human mesothelium were published [2]. In the succeeding years there has been a quickening of interest in peritoneal ultrastructure, both in regard to a furthering of our understanding of what structures are interposed between the capillary bed and the dialysate, as well as a developing awareness of changes associated with the process of dialysis.

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Authors
  1. James W. Dobbie
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Editors and Affiliations

  1. Department of Renal Medicine, Manchester Royal Infirmary, Manchester, UK

    Ram Gokal

  2. Division of Nephrology, Department of Internal Medicine, School of Medicine, University of Missouri, Health Sciences Center and Dalton Cardiovascular Research Center, Columbia, Missouri, USA

    Karl D. Nolph

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© 1994 Springer Science+Business Media Dordrecht

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Dobbie, J.W. (1994). Ultrastructure and pathology of the peritoneum in peritoneal dialysis. In: Gokal, R., Nolph, K.D. (eds) The Textbook of Peritoneal Dialysis. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0814-0_2

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  • DOI: https://doi.org/10.1007/978-94-011-0814-0_2

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-4349-6

  • Online ISBN: 978-94-011-0814-0

  • eBook Packages: Springer Book Archive

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