Skip to main content

Extrabiotic Replication and Self-Assembly

  • Chapter
Self-Production of Supramolecular Structures

Part of the book series: NATO ASI Series ((ASIC,volume 446))

  • 232 Accesses

Abstract

Experimental studies of self-replicating organic molecules are described, and the use of synthetic replicators to study the effects of environmental stresses and recombination is defined. Complementarity and self-complementarity of size, shape, and chemical surface are shown to influence this behavior. In addition, molecular capsules are assembled from self-complementary pieces. It is intended ultimately to combine the capsules with self-replicating molecules.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Askew B, Ballester P, Buhr C, Jeong KS, Jones S, Parris K, Williams K, Rebek J Jr. 1989. Molecular recognition with convergent functional groups VI: Synthetic and structural studies with a model receptor for nucleicacid components.J Am Chem Soc 111:1082–1090.

    Article  CAS  Google Scholar 

  • Barr RG, Pinnavaia TJ. 1986. Solution ordering of guanosine 2’ monophosphate dianions with alkali metal ions as structure directors, J Chem Phys 90:328–334.

    Article  CAS  Google Scholar 

  • Deslongchamps G, Galán A, de Mendoza J, Rebek J Jr.1992.A synthetic receptor for cyclic AMP. Angew Chem Int Ed Engl 31:61–63.

    Article  Google Scholar 

  • Feng Q, Park TK, Rebek J Jr.1992.Crossover reactions between synthetic replicators yield active and inactive recombinants.Science 256:1179– 1180.

    Article  CAS  Google Scholar 

  • Freeman HJ.1980. The Eighth Day of Creation.Simon and Schuster, New York.

    Google Scholar 

  • Galán A, de Mendoza J, Toiron C, Bruix M, Deslongchamps G, Rebek J Jr. 1991.A synthetic receptor for dinucleotides. f Am Chem Soc 113:9424– 9425.

    Article  CAS  Google Scholar 

  • Hong J-I, Feng Q, Rotello V, Rebek J Jr. 1992. Competition, cooperation and mutation at the molecular level: Improvement of a synthetic replicator by light irradiation. Science 255:848–850.

    Article  CAS  Google Scholar 

  • Levy S.1992. Artificial Life: The Quest for a New Creation.Pantheon, New York.

    Google Scholar 

  • Lewin R.1992. Complexity: Life at the Edge of Chaos. Macmillan, New York.

    Google Scholar 

  • Park TK, Schroeder J, Rebek J Jr.1991. New molecular complements to imides.Complexation of thymine derivatives.J Am Chem Soc 113: 5125–5127.

    Article  CAS  Google Scholar 

  • Park TK, Feng Q, Rebek J Jr.1992. Synthetic replicators and extrabiotic chemistry. J Am Chem Soc 114:4530–4532.

    Google Scholar 

  • Rebek J Jr.1992.Synthetic replicators and extrabiotic chemistry.Chem & Ind 171–174.

    Google Scholar 

  • Rotello V, Hong J-I, Rebek J Jr.1991. Sigmoidal growth in a self-replicating system. J Am Chem Soc 113: 9422–9423.

    Article  CAS  Google Scholar 

  • Rotello V, Viani EA, Deslongchamps G, Murray BA, Rebek J Jr.1993. Molecular recognition in water: New receptors for adenine derivatives. J Am Chem Soc 115: 797–798.

    Article  CAS  Google Scholar 

  • Tjivikua T, Ballester P, Rebek J Jr.1990.A self-replicating system.J Am Chem Soc 112: 1249–1250.

    Article  CAS  Google Scholar 

  • von Kiedrowski G.1986.A self-replicating hexadeoxynucleotide.Angew Chem Int Ed Engl 98:932.

    Article  Google Scholar 

  • von Kiedrowski G, Wlotzka B, Helbing J, Mattzen M, Jordan S.1991. Parabolic growth of a self-replicating hexadeoxynucleotide bearing a 3’5’ phosphoamidate linkage. Angew Chem Int E Engl 30: 423.

    Article  Google Scholar 

  • Whitesides GM, Mathias JP, Seto CT.1991.Molecular self-assembly and nanochemistry: A chemical strategy for the synthesis of nanostructures. Science 254:1312–1319.

    Article  CAS  Google Scholar 

  • Wyler R, de Mendoza J, Rebek J Jr.1993. A synthetic cavity assembles through self-complementary hydrogen bonds.Angew Chem Int Ed Engl: (In press).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1994 Springer Science+Business Media Dordrecht

About this chapter

Cite this chapter

Rebek, J. (1994). Extrabiotic Replication and Self-Assembly. In: Fleischaker, G.R., Colonna, S., Luisi, P.L. (eds) Self-Production of Supramolecular Structures. NATO ASI Series, vol 446. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0754-9_6

Download citation

  • DOI: https://doi.org/10.1007/978-94-011-0754-9_6

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-4324-3

  • Online ISBN: 978-94-011-0754-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics