Abstract
Desipramine is a tricyclic antidepressant with actions and uses similar to amitriptyline but with reduced sedating and antimuscarinic properties. It is the principal active metabolite of imipramine. The plasma half-life varies from 10 to 35 hours as a result of inter-subject variability in metabolism. The therapeutic range in plasma is 0.07-0.2 μg/ml. Monitoring is valuable only in patients with a diagnosis of endogenous depression.
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© 1995 Springer Science+Business Media New York
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Wilson, J.F. (1995). Desipramine. In: Wilson, J.F. (eds) Drugs Eicosanoids. Immunoassay Kit Directory, vol 1 / 3 / 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0679-5_13
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DOI: https://doi.org/10.1007/978-94-011-0679-5_13
Publisher Name: Springer, Dordrecht
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