Abstract
The human-human hybridoma AE6F4 established by Shoji et al. (submitted) can produce monoclonal antibody which specifically binds with an antigen site on lung cancer cells. An effective strategy is required to produce the monoclonal antibody rationally under the optimum production conditions. Many researchers have investigated the growth and monoclonal antibody production kinetics of hybridoma cells to improve and optimize the monoclonal antibody productivity (Miller et al., 1988, McQueen and Bailey, 1990, Glacken, 1988). It is important to examine the effects of external culture conditions such as pH and DO on the hybridoma growth and monoclonal antibody production because it is easy to control the external culture condition.
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© 1995 Springer Science+Business Media Dordrecht
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Shirai, Y., Yamaguchi, M., Murakami, H. (1995). Culture Conditions for High Performance Production of Monoclonal Antibody. In: Beuvery, E.C., Griffiths, J.B., Zeijlemaker, W.P. (eds) Animal Cell Technology: Developments Towards the 21st Century. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0437-1_52
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DOI: https://doi.org/10.1007/978-94-011-0437-1_52
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