Abstract
Numerous environmental risks damage the reproductive system, causing various negative outcomes. Research in this area has emphasized the study of congenital malformations. Other negative outcomes, however, such as embryonic loss, pre- or post-implantation, might be considered significant, because of their severity from the biological point of view and their more frequent occurrence. It is estimated, for example, that 60–70% of all conceptions terminate in spotaneous abortion (Roberts and Lowe, 1975).
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References
Ad Hoc Committee on the Effects of Trace Anesthetics (1974). Occupational disease among operating room personnel: a national study. Anesthesiology, 41, 321–340
Ando, Y. and Hattori, H. (1977). Effects of noise on human placental lactogen (HPL) levels in maternal plasma. Br. J. Obstet. Gynaecol., 84, 115
Angeli, A. (1980). Ritmi endocrini in rapporto all’alternanza sonnoveglia. Atti del Simposio Nazionale Lavoro a Turni Cronobiologia e Protezione della Salute, Verona, 14 marzo 1980
Baden, J. and Monk, S. (1981). Mutagenicity and toxicity studies with high pressure nitrous oxide. Toxicol. Lett., 7, 259
Berlinguer, G., Figa-Talamanca, I. and Schirripa, P. (1981). Indagine sulla salute riproduttiva delle lavoratrici dell’artigianato. Epideminol. Prevenz., 14, 53
Berman, E., Kinn, J. B. and Carter, H. B. (1978). Observations of mouse fetuses after irradiation with 2.45 GHz microwave radiation. Health Phys., 35, 791
Bohm, F. (1964). The effect of vehicle vibration on the genitalia of female driving personnel. Z. Gesamte Hyg., 10, 720
Calvin, C. W., Ferm, V. H. and Smith, R. P. (1981). Teratogenic effects of aliphatic nitriles. Teratology, 23, 317
Carosi, L. and Calabro, F. (1968). Fertilitâ di coppie esposte a rumore industriale. Folia Med., 51, 264
Cavanagh, J. B. and Bennetts, R. J. (1981). On the patterns of changes in the rat nervous system produced by 2,5 hexanediol. Brain, 104, 297
Christianson, R., Van den Berg, J. Milkovich, L. and Oechsli F. W. (1981). Anomalies among white and black live births with long term follow up. Am. J. Public Health, 71, 1333
Cohen, E. N., Gift, H. C., Brown, B. W., Greenfield, W., Wu, M. L., Jones, T. W., Whitcher, C. E., Driscoll, E. J. and Brodsley, J. B. (1980). Occupational disease in dentistry and chronic exposure to trace anesthetic gases. J. Am. Dent. Assoc., 101, 21
Cook, R. O. (1979). Effects of prenatal noise exposure in the learning level of guinea pigs. Environ. Health Perspect., 33, 341
Corbett, T. H. (1976). Cancer and congenital anomalies associated with anesthetics. Ann. NY Acad. Sci., 271, 58
Corbett, T. H., Cornell, R. G., Endres, J. L. and Lieding, K. (1974). Birth defects among children of nurse anesthetists. Anesthesiology, 41, 341
DHSS (Department of Health and Social Security) (1981). Guidelines for the testing of chemicals for mutagenicity. Report on Health and Social Subjects, 24. ( London: HMSO )
Dreyer, N. A. and Friedlander, E. (1982). Identifying the health risks from very low dose sparsely ionizing radiation. Am. J. Public Health, 72, 585
Dukes-Dobos, F. N. (1981). Hazards of heat exposure. A review. Scand. J. Work Environ. Health, 7, 73
Edling, C. (1980). Anesthetic gases as an occupational hazard. A review. Scand. J. Work Environ. Health, 6, 85
Edmonds, L. D., Anderson, C., Flynt, J. W. and James, L. M. (1978). Congenital central nervous system malformations and vinyl chloride monomer exposure: a community study. Teratology 17, 137
Fabia, J. and Thuy, T. B. (1974). Occupation of father at time of birth of children dying of malignant diseases. Br. J. Prey. Soc. Med., 28, 98
Figa-Talamanca, I. (1981). Indagine epidemiologica sugli esiti riproduttivi del personale femminile esposto ai rischi nell’ambiente ospedaliero. Quaderni Stat. San., IV, 1
Frolova, T. P. (1975). Features specific for the effect of vibration on the pelvis at different periods in the menstrual cycle. Gig. Truda Prof Zabol., 19, 14
Gerber, G. B., Léonard, A. and Jacquet, P. (1980). Toxicity; mutagenicity and teratogenicity of lead. Mutat. Res., 76, 115
Gilani, S. H. and Marano, M. (1980). Congenital abnormalities in nickel poisoning in chick embryos. Arch. Environ. Contam. Toxicol., 9, 17
Goud, S. N., Rani, V., Réddy, P. P., Saddi, O. S., Rao, M. S. and Saxeno, V. K. (1982). Genetic effects of microwave radiation in mice. Mutat. Res., 103, 39
Granati, A. and Lenzi, R. (1976). Lavoro e funzione di maternitâ. 39° Congresso Nazionale della Societk Italiana di Medicina del Lavoro e di Igiene Industriale, Fiuggi, 16–18 sett., Ist. Med. Sociale, Roma
Gratsianskaya, L. N., Eroshenko, E. A. and Libertovich, A. P. (1974). Influence of high-frequency vibration on the genital region in females. Gig. Truda Prof. Zabol., 18, 70
Harlap, S. and Shiono, P. H. (1980). Alcohol smoking and incidence of spontaneous abortion in the first and second trimester. Lancet, 2, 173
Hemminki, K. (1980). Occupational chemicals tested for teratogenicity. Int. Arch. Occup. Environ. Health, 47, 191
Hemminki, K., Niemi, M. L., Saloniemi, I., Vainio, H. and Hemminki, E. (1980). Spontaneous abortion by occupation and social class in Finland. Int. J. Epidemiol., 9, 149
Hemminki, K., Saloniemi, I., Salonem, T., Portanen, T. and Vainio, H. (1981). Childhood cancer and parental occupation in Finland. J. Epidemiol. Community Health, 35, 11
Himmelberger, D., Byron, W., Brown, E. and Cohen, E. (1978). Cigarette smoking during pregnancy and the occurrence of spontaneous abortion and congenital abnormality. Am. J. Epidemiol., 108, 470
Hoffman, D. C. and Wynder, E. L. (1976). Smoking and occupational cancers. Prey. Med., 5, 245
Hoffmann, D. J. and Cambell, K. I. (1977). Postnatal toxicity of carbon monoxide after pre and post natal exposure Toxicol. Lett., 1, 147
Hook, E. (1981). Prevalence of chromosome abnormalities during human gestation and implications for studies of environmental mutagens. Lancet, 2, 169
Hunt, R. V. (1979). Work and the Health of Women, pp. 105–107.
Boca Raton, FI: CRC Press Hunt, V. (1978). Occupational radiation exposure of women workers. Prey. Med., 7, 294
Infante, P. F. (1980). Chloroprene: adverse effects on reproduction. In Proceedings of a Workshop on Methodology for Assessing Reproductive Hazards in the Workplace, pp. 87–101. US DHHS (NIOSH) Publication no. 81–100
Infante, P. F., Wagonen, J. K. and Waxweiler, R. J. (1976). Carcinogenic, mutagenic and teratogenic risks associated with vinyl chloride. Mutat. Res., 41, 131
Infante, P. F., Epstein, S. S. and Newton W. A. (1978). Blood dyscrasias and childhood tumors and exposure to chlordane and heptachlor. Scand. J. Work Environ. Health, 4, 137
Inouye, M., Galvin, M. and McRee, D. (1982). Effects of 2.45 GHz microwave radiation on the development of Japanese quail cerebellum. Teratology, 25, 115
Jacquet, P. and Gerber, G. B. (1977) Plasma hormone levels in normal and lead treated mice. Experientia, 33, 1375
John, J. A., Smith, F. A., Leong, B. K. J and Schwetz, B. A. (1977). The effects of maternally inhaled vinyl chloride on embryonal and fetal development in mice, rats and rabbits. Toxicol. Appl. Pharmacol., 39, 497
Jones, F. N. (1978). Residence under an airport landing pattern as a factor in teratism. Arch. Environ. Health, 33, 10
Kantor, A. F., McCrea Curner, M. G., Meigs, J. W. and Flannery, J. T. (1979). Occupations of fathers of patients with Wilm’s tumor. J. Epidemiol. Commun. Health, 33, 253
Karatsune, M., Yoshimura, T., Matzuzaka, J. and Yamaguchi, A. (1972). Epidemiologic study on Yusho, a poisoning caused by ingestion of rice oil contaminated with a commercial brand of polychlorinated biphenyls. Environ. Health Perspect., 1, 119
Khera, A. K., Wibberly, D. G. and Dathan, J. G. (1980). Placental and stillbirth tissue lead concentrations in occupationally exposed women. Br. J. Ind. Med., 37, 394
Kline, A. J., Stein, S., Susser, M. and Warburton, D. (1977). Smoking: a risk factor for spontaneous abortion. N. Engl. J. Med., 297, 793
Knecht, E. A., Wright, G. L. and Toraason, M. A. (1978). Periodic short-term heat exposure in male and female rats. Can. J. Physiol. Pharmacol., 56, 747
Knill-Jones, R. P., Moir, D. B., Rodrigues, L. V. and Spence A. A. (1972). Anaesthetic practice and pregnancy: a controlled study of women anaesthesists in the U.K. Lancet, 1, 1326
Knill-Jones, R. P., Newman, B. J. and Spence, A. A. (1975). Anaesthetic practice in pregnancy: a controlled survey of male anaesthesists in the U.K. Lancet, 2, 807
Koos, B. J. and Longo, L. D. (1976). Mercury toxicity in pregnant women, fetus and new born infant. Am. J. Obstet. Gynecol., 1, 390
Krasovskii, G. N., Varshayskaya, S. P. and Borisova, A. F. (1976). Toxicologic and gonadotropic effects of cadmium and boron relative to standard of these substances in drinking water. Environ. Health Perspect., 13, 69
Krauthacker, B., Alebic-Kolbah, T., Buntíc, A., Tkatevé, B. and Reiner, E. (1980). DDT residues in samples of human milk and mother’s and cord blood serum, in a continental town in Croatia (Yugoslavia). Int. Arch. Occup. Environ. Health, 46, 267
Kuna, R. A. and Karpt, R. W. (1981). The embryotoxic teratogenic potential of benzene vapor in rats. Toxicol. Appl. Pharmacol., 57, 1
Kupfer, D. and Bulger, W. H. (1976). Interactions of chlorinated hydrocarbons with steroid hormones. Fed. Proc., 35, 2603
La Bella, F. S., Dular, R., Vivian, S. and Queen, G. (1973). Prolactin secretion is specifically inhibited by nickel. Nature (Lond.), 245, 330
Lancranjan, I. (1972). Alterations of spermatic liquid in patients chronically poisoned by carbon disulfide. Med. Lay., 63, 29
Lancranjan, I., Papescu, H. I., Gavanesu, O., Klepsch, I. and Sabanescu, M. (1975a). Reproductive ability of workmen occupationally exposed to lead Arch. Environ. Health, 30, 396
Lancranjan, I., Maicanescu, M., Rafaila, E., Klepsch, I. and Popescu, H. I. (1975b). Gonadic function in workmen with long-term exposure to micro-waves. Health Phys., 29, 381
Land, P. C., Owen, E. L. and Linde, H. W. (1979). Mouse sperm morphology following exposure to anesthetics during early spermatogenesis. Anesthesiology, 51, Suppl. S259
Lane, G. A., Nahrwold, M. L., Tait, A. R., Taylor, B. S., Beaudoin, A. R. and Chonen, P. J. (1979). ‘Nitrous oxide is teratogenic: xenon is not!’ Anesthesiology, 51, Suppl. S260
Lauwerys, R., Roels, H. and Hubermont, G. (1978). Placental transfer of lead mercury, cadmium and monoxide in women. I. comparison of the frequency distribution of the biological indices in maternal and umbilical cord blood. Environ. Res., 15, 278
Leach, W. M. (1980). Genetic growth and reproductive effects of micro-wave radiation. Bull, NY Acad. Med., 56, 249
Lee, I. P. and Dixon, R. L. (1975). Effects of mercury on spermatogenesis studied by velocity sedimentation cell separation and serial mating. J. Pharmacol. Exp. Ther., 194, 171
Lee, I. P., Shering, R. J. and Dixon, R. L. (1978). Evidence for induction of germinal aplasia in male rats by environmental exposure to boron. Toxicol. App!. Pharmacol., 23, 557
Levin, A. A. and Miller, R. K. (1981). Fetal toxicity of cadmium in rats: decreased utero-placental blood flow, Toxicol. Appl. Pharmacol., 58, 297
McDonald, H. D. (1958). Women at work. Maternal health and congenital defects. A prospective investigation. N. Engl. J. Med., 258, 767
Maltoni, C. and Lefemine, G. (1974). Le potenzialita dei saggi sperimentali nella predizione dei rischi oncogeni ambientali. Un esempio: it cloruro di vinile. Rend. Sci. Fis. Mat. Nat. (Lincei), 66, 1
Manson, J. and Simons, R. (1979). Influence of environmental agents on male reproductive failure. In Hunt, V. (ed.) Work and the Health of Women, pp. 155–175. ( Boca Raton. FI: CRC Press )
Mansour, M., Dyer, N., Hoffman, L., Schulert, A. and Brill, A. (1973). Maternal fetal transfer of organic and inorganic mercury via placenta and milk. Environ. Res., 6, 479
Masatoshi, F., Toyoaki, F. and Shuichi, H. (1978). Embriotoxic effects of methylmercuric chloride administered to mice and rats during organogenesis. Teratology, 18, 353
Mauks, T. A., Kimmel, G. L. and Staplest, R. E. (1981). Influence of symmetrical polychlorinated biphenyl isomers on embryo and fetal development in mice. Toxicol. App!. Pharmacol., 61, 269
Messerle, K. and Webster, W. S. (1982). The classification and development of cadmium induced limb defects in mice. Teratology, 25, 61
Nikitina, Y. I. (1974). Course of labor and puerperium in the vineyard workers and milkmaids in Crimea. Gig. Truda Prof Zabol., 18, 17
NIOSH (1977). Criteria for a Recommended Standard… Occupational Exposure to PCBs. DHEW (NIOSH) Publication no 77–225
NIOSH (1978). Special Occupational Hazard Review DDT. DHEW (NIOSH) Publication no. 78–200, 78–85
Panova, Z. (1972). Early changes in the ovarian function of women in occupational contact with inorganic lead. Works of the United Research Institute of Hygiene and Industrial Safety, Sofia, Bulgaria, 161–166
Paìízek, J. (1964). Vascular changes at sites of oestrogen biosynthesis produced by parenteral injection of cadmium salts: the destruction of placenta by cadmium salts. J. Reprod. Fertil., 7, 263
Parker, K. and Sunderman, W. (1974). Distribution of 63Ni in rabbit tissues following intravenous injection of fi3Ni C12. Res. Commun. Chem. Pathol. Pharmacol., 7, 755
Petrov, M. V. (1969). Some data on the course and termination of pregnancy in female workers of the viscose industry. Pediatr. Akush. Gynekol., 3, 50
Pharoah, P. O. D., Alberman, E., Doyle, P. and Chamberlain, G. (1977). Outcome of pregnancy among women in anesthetic practice. Lancet, 1, 34
Preston, F. S., Bateman, S. L., Short, R. V. and Wilkinson, R. T. (1973). Effects of time changes on the menstrual cycle length and on performance in airline stewardesses. Aerospace Med., 44, 438
Reiber-Strobino, B., Kline, J. and Stein, Z. (1978). Chemical and physical exposure of parents: effects on human reproduction and offspring. J. Early Hum. Dev., 1, 371
Roberts, C. J. and Lowe, C. R. (1975). Where have all the conceptions gone? Lancet, 1, 498
Rom, W. (1980). Effect of lead on reproduction. In Proceedings of a Workshop on Methodology for Assessing Reproductive Hazards in the Workplace, pp. 33–40. US DHHS (NIOSH) Publication no. 81–100
Rosenberg, P. and Kirves, A. (1973). Miscarriages among operating theatre staff. Acta Anaesthesiol. Scand. Suppl., 53, 37
Rosenberg, P. H. and Vanttienen, H. (1978). Occupational hazards to reproduction and health in anesthetists and pediatricians. Acta Anaesthesiol. Scand., 22, 202
Samoilova, G. S. and Marinova, G. (1978). Effect of industrial vibration on specific functions of a woman’s body. Gig. Sant., 6, 27
Singh, K. B. (1972). Effect of sound on the female reproductive system. Am. J. Obstet. Gynecol., 112, 981
Smith, R., Bowman, R. E. and Katz, J. (1978). Behavioural effects of exposure to halothane during early development in the rat. Anesthesiology, 49, 319
Spyker, J. M. and Smithberg, M. (1971). Effects of methylmercury on prenatal development in mice. Teratology, 5, 181
Staples, R. E. (1975). Teratogenic potential of noise in mice and rats. Toxicol. Appl. Pharmacol., 33, 123
Stellman, J. and Stellman, S. (1980). Health effects of radiofrequency radiation in a cohort of physical therapists. Am. J. Epidemiol., 112, 442
Sunderman, F. W., Shen, S. K., Mitchell, J. M., Allpass, P. R. and Damjanov, I. (1978). Embryotoxicity and fetal toxicity of nickel in rats. Toxicol. Appl. Pharmacol., 43, 381
Sunderman, F. W. Jr., Allfais, P. R., Mitchell, J. M., Baselt, R. C. and Albert, D. M. (1979). Eye malformations in rats. Induction by prenatal exposure to nickel carbonyl. Science, 203, 550
Tabacova, S., Hinkova, L. and Balaboeva, L. (1978). Carbon disulphide teratogenicity and postnatal effects in rats. Toxicol. Lett., 2, 129
Tabacova, S., Hinkova, L., Nikiforov, B. and Balaboeva, L. (1981). Hazards for the progeny after maternal exposure to low carbon disulphide concentrations. G. Ital. Med. Lay., 3, 121
Terada, M. (1974). Effects of physical activity before pregnancy on fetuses of mice exercised forcibly during pregnancy. Teratology, 10, 141
Tsvetkova, R. P. (1970). Influence of cadmium compounds on the generative function. Gig. Truda Prof. Zabol.., 14, 31
Underwood, P. B., Hester, L. L., Lafittee, J. Jr. and Gregg, K. V. (1965). The relationship of smoking to the outcome of pregnancy. Am. J. Obstet. Gynecol., 91, 270
UN Scientific Committee on the Effects of Atomic Radiation (1977). Report. Sources and Effects of Ionizing Radiation. ( New York: UN )
US DHEW (Department of Health, Education and Welfare) (1976). Health Consequences of Smoking. ( Washington: US Govt. Printing Office )
Varma, M. M., Joschi, S. R. and Adeyemi, A. O. (1974). Mutagenicity and infertility following administration of lead subacetate to Swiss male mice. Experientia, 30, 486
Vasilyeva, I. A. (1973). Effects of small concentration of carbon disulfide and hydrogen sulfide on the menstrual function of women and the estrus cycle of experimental animals. Gig. Sant., 7, 24
Wägar, G., Tolonen, M. and Helpio, E. (1981). Endocrinological studies of Finnish viscose rayon workers exposed to carbon disulfide. G. Ital. Med. Lay., 3, 103
Wagoner, K. J. and Infante, P. F. (1980). A review of the methodologic approach in the assessment of the association between vinyl chloride exposure and reproductive hazards. In Proceedings of a Workshop on Methodology for Assessing Reproductive Hazards in the Workplace, pp. 43–49. US DHHS (NIOSH) Publication no. 81–100
Waltscheva, V., Slateva, M. and Michailov, I. V. (1972). Testicular changes due to long-term administration of nickel sulfate. Pathol. Exp., 6, 116
Wharton, R., Mazze, R., Baden, J. M., Hitt, B. A. and Dooley, J. R. (1978). Fertility, reproduction and postnatal survival in mice chronically exposed to halothane. Anesthesiology, 48, 167
Wharton, R., Mazze, R. and Wilson, A. (1981). Reproductive and fetal development in mice chronically exposed to enflurane. Anesthesiology, 54, 505
Whorton, D. (1980). Dibromochloropropane (DBCP). In Proceedings of a Workshop on Methodology for Assessing Reproductive Hazards in the Workplace, pp. 103–109. US DHHS (NIOSH) Publication no. 81–100
Wide, M. and Nebon, O. (1977). Differential susceptibility of the embryo to inorganic lead during preimplantation in the mouse. Teratology, 16, 273
Yakushiji, T., Watanabe, K., Kuwabara, S., Yoshida, K. Koyama and Kunita, N. (1979). Levels of polychlorinated biphenyls (PCBs) and organochlorine pesticides in human milk and blood collected in Osaka Prefecture from 1972 to 1977. Int. Arch. Occup. Environ. Health, 43, 1
Youdzik, M. (1971). Histology and histochemistry of rat testicles as affected by carbon disulphide. Pol. Med. J., 10, 133
Zucher, I. and Charmichael, M. (1981). Circadian rhythms, brain peptides and reproduction. In Martin, J. B., Reichlin, S. and Bick, K. L. (eds.) Neurosecretion and Brain Peptides, pp. 459–473. ( New York: Raven Press )
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Figá-Talamanca, I., Settimi, L. (1984). Occupational factors and reproductive outcome. In: Hafez, E.S.E. (eds) Spontaneous Abortion. Advances in Reproductive Health Care, vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-9789-5_5
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