Abstract
It has been shown that non-steroidal anti-inflammatory drugs (NSAID’s) through their inhibition of prostaglandin synthesis, can attenuate the effects of anti-hypertensive and diuretic agents1–7. The clinical relevance and therapeutic implications of these findings are not clear at the present time due to the fact that there are large discrepancies between the findings themselves and their interpretation by the respective authors. There is, particularly, very little mention of the fact that there are responders and non-responders to that drug interaction, and very little attention has been given to protocol details that may be necessary to explain the effects observed.
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Sörgel, F., Koob, R., Hemmerlein, M., Braun, J., Lang, E. (1987). Responders and non-responders to NSAI drug interactions — a neglected problem?. In: Rainsford, K.D., Velo, G.P. (eds) Side-Effects of Anti-Inflammatory Drugs. Inflammation and Drug Therapy Series, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-9772-7_16
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DOI: https://doi.org/10.1007/978-94-010-9772-7_16
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