Abstract
Inflammatory changes in the skin are a common feature of many skin disorders; similar changes also occur after trauma to the skin particularly after burns. In some instances there is increased pigmentation (Figure 33), whilst in others there is decreased pigmentation (Figure 34). Increased pigmentation may be due to stimulation of melanocytes and/or retention of melanin granules in the upper dermis in macrophages after there has been destruction of the basal layer of the epidermis. Hypopigmentation may be due to inhibition of melanocyte function, loss of melanocytes due to rapid turnover of the epidermis as in psoriasis, or alteration of the keratinocytes in which they are unable to take up melanin granules.
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© 1985 L. Fry and M. N. P. Cornell
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Fry, L., Cornell, M.N.P. (1985). Disorders Of Pigmentation. In: Dermatology. Management of Common Diseases in Family Practice. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-9228-9_16
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DOI: https://doi.org/10.1007/978-94-010-9228-9_16
Publisher Name: Springer, Dordrecht
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