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Synthesis of Polyesters by Lipase-Catalyzed Polycondensation in Organic Media

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Biocatalysis

Part of the book series: Van Nostrand Reinhold Catalysis Series ((NRECSES))

Abstract

During the past 5 years, research arising from the pioneering work of Klibanov and co-workers (Zaks and Klibanov 1984; Klibanov 1986) has led to enzyme-catalyzed reactions in anhydrous, organic media taking their place as valuable tools for synthetic organic chemistry. Among the useful processes involving hydrolytic enzymes are esterifications (Gatfield 1984; Cambou and Klibanov 1984b; Zaks and Klibanov 1985; Kirchner, Scollar, and Klibanov, 1985; Langrand et al. 1985, 1986; Chen et al. 1987; Hemmerle and Gais 1987; Gil et al. 1987; Sonnet 1987; Bianchi, Cesti, and Battistel 1988; Yamamoto, et al., 1988), transesteri-fications (Cambou and Klibanov 1984a, b; Zaks and Klibanov 1985; Kirchner, Scollar, and Klibanov 1985; Ramos Tombo et al. 1986; Belan et al. 1987; Degueil-Castaing et al. 1987; Njar and Caspi 1987; Francalanci et al. 1987; Stokes and Oehlschlager 1987; Riva and Klibanov 1988; Theisen and Heathcock 1988; Wang and Wong 1988; Wang et al. 1988; Abramowicz and Keese 1989), aminolyses (Zaks and Klibanov 1985; Margolin and Klibanov 1987; West and Wong 1987; Kitaguchi et al. 1989), and lactonizations (Makita, Nihira, and Yamada 1987; Gutman, Zuobi, and Boltansky 1987; Guo and Sih 1988). Most of these transformations have been shown to occur with remarkable regio- and/or enantioselectivity.

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  1. Cary J. Morrow
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  2. J. Shield Wallace
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  1. Biological Sciences Laboratory, General Electric Company, Schenectady, New York, USA

    Daniel A. Abramowicz Ph.D. (Manager of Environmental Technology) (Manager of Environmental Technology)

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Morrow, C.J., Wallace, J.S. (1990). Synthesis of Polyesters by Lipase-Catalyzed Polycondensation in Organic Media. In: Abramowicz, D.A. (eds) Biocatalysis. Van Nostrand Reinhold Catalysis Series. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-9124-4_2

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  • DOI: https://doi.org/10.1007/978-94-010-9124-4_2

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