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Decompression Sickness

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Space Clinical Medicine
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Abstract

Past experience has indicated that astronauts may be exposed to a risk of decompression sickness during extravehicular operations which require decompression from an atmosphere containing an inert gas. This will also be the case following an emergency or accidental decompression of an atmosphere containing inert gas to an ambient pressure at which death does not immediately result from acute hypoxia (Chapter 1) or the combined effects of acute hypoxia and ebullism (Chapter 2).

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References

  1. Adler, H.F.: 1950, Neurocirculatory Collapse at Altitude. Special Project, U.S. Air Force Sch. Aviation Med., Randolph Field, Texas.

    Google Scholar 

  2. Adler, H.F.: 1964, Dysbarism, AF-SAM-Rev-1-64, U.S. Air Force Sch. Aviation Med., Brooks AFB, Texas.

    Google Scholar 

  3. Andersen, H.R.: 1965, A Historical Review of the Bubble Theory of the Etiology of Decompression Sickness as Related to High Altitude Exposure. AF-SAM-Rev-10-65, U.S. Air Force Sch. Aerospace Med., Brooks AFB, Texas.

    Google Scholar 

  4. Anthony, R. A., Clarke, R.W., Liberman, A., et al.: 1943, Temperature and Decompression Sickness. NAS-NRC-CAM-136, National Academy of Sciences - National Research Council, Committee on Aviation Medicine, Washington, D.C.

    Google Scholar 

  5. Barthelemy, L.: 1963, ‘Blood Coagulation and Chemistry During Experimental Dives and the Treatment of Diving Accidents with Heparin’, in Proceedings Second Symposium on Underwater Physiology, NAS-NRC-1181, National Academy of Sciences - National Research Council, Washington, D.C., pp. 46–56.

    Google Scholar 

  6. Beard, S.E., Allen, T.H., McIver, R.G., and Bancroft, R. W.: 1967, ‘Comparison of Helium and Nitrogen in Production of Bends in Simulated Orbital Flights’, Aerospace Med. 38, 331–337.

    PubMed  CAS  Google Scholar 

  7. Behnke, A.R.: 1947, A Review of the Physiologic and Clinical Data Pertaining to Decompression Sickness. NMRI-443-4, U.S. Naval Medical Research Inst., Bethesda, Md.

    Google Scholar 

  8. Behnke, A. R.: 1951, ‘Decompression Sickness Following Exposure to High Pressures’, in Decompression Sickness (ed. by J.G. Fulton ). W.B. Saunders Co., Philadelphia, pp. 53–89.

    Google Scholar 

  9. Berry, C. A.: 1961, ‘Dysbarism: An Inflight Case and a Discussion of the Present Status’, Aerospace Med. 32, 107–112.

    Google Scholar 

  10. Berry, C. A. and Smith, M.R.: 1962, ‘Recent U.S.A.F. Experience with Inflight Dysbarism’, Aerospace Med. 33, 995–1000.

    PubMed  CAS  Google Scholar 

  11. Blinks, L.R., Twitty, V.C., and Whitaker, D.M., ‘Part II. Bubble Formation in Frogs and Rats’, in Decompression Sickness (ed. by J.G. Fulton), W.B. Saunders Co., Philadelphia, pp. 145–164.

    Google Scholar 

  12. Boothby, W. M., Lovelace, W.R., and Benson, O. O., cited by Ferris, E.B., Jr. and Engel, G.L. (see ref. 36).

    Google Scholar 

  13. Bratt, H.R.: 1962, ‘Report of a Case of Severe Dysbarism Treated with a Recompression Chamber’, Aerospace Med. 33, 358.

    Google Scholar 

  14. Brunner, F.P., Frick, P.G., and Buhlmann, A.A.: 1964, ‘Post-Decompression Shock Due to Extravasation of Plasma’, Lancet 1, 1071–1073.

    Article  PubMed  CAS  Google Scholar 

  15. Busby, D.E.: 1962, Unpublished Observations. Lovelace Foundation for Medical Education and Research, Albuquerque, N.M.

    Google Scholar 

  16. Burkhardt, W.L., Adler, H., and Thometz, A.F.: 1946, ‘A Roentgenographic Study of “Bends” and Chokes at Altitude’, J. Aviat. Med. 17, 462–477, 482.

    PubMed  CAS  Google Scholar 

  17. Cannon, P. and Gould, T.R., ‘Treatment of Severe Decompression Sickness in Aviators’, Brit. Med. J. 1, 278–282.

    Google Scholar 

  18. Catchpole, H.R. and Gersh, I.: 1947, ‘Pathogenetic Factors and Pathological Consequences of Decompression’, Physiol. Rev. 27, 360–397.

    PubMed  CAS  Google Scholar 

  19. Clay, J.R.: 1963, ‘Histopathology of Experimental Decompression Sickness’, Aerospace Med. 34, 1107–1110.

    PubMed  CAS  Google Scholar 

  20. Clamann, H. G.: 1961, ‘Decompression Sickness’, in Aerospace Medicine (ed. by H.G. Armstrong ). Williams and Wilkins, Baltimore, pp. 175–188.

    Google Scholar 

  21. Coburn, K.R., Gould, T.R., and Young, J.M.: 1962, ‘Decompression Collapse Syndrome: Report of a Case with Successful Treatment by Compression to a Pressure in Excess of One Atmosphere’, Aerospace Med. 33, 1211–1215.

    PubMed  CAS  Google Scholar 

  22. Cockett, A.T. K. and Nakamura, R. M.: 1964, ‘Newer Concepts in the Pathophysiology of Experimental Dysbarism - Decompression Sickness’, Amer. Surg. 30, 447–451.

    CAS  Google Scholar 

  23. Cockett, A.T.K., Nakamura, R.M., and Franks, J. J.: 1963, ‘Delayed Shock in Experimental Dysbarism’, Surg. Forum 14, 7–8.

    PubMed  CAS  Google Scholar 

  24. Cockett, A.T.K., Nakamura, R. M., and Kado, R.T.: 1966, ‘Physiological Factors in Decompression Sickness’, Arch. Environ. Health 11, 760–764.

    Google Scholar 

  25. Cook, S.F., Williams, O.L., Lyons, W.R. and Lawrence, J.H.: 1944, Comparison of Altitude and Exercise with Respect to Decompression. NAS-NRC-CAM-245, National Academy of Sciences - National Research Council, Committee on Aviation Medicine, Washington, D.C.

    Google Scholar 

  26. Cotes, F.L.: 1953, Decompression Sickness with Post-Decompression Collapse. Flying Personnel Research Committee, Royal Air Force Institute of Aviation Medicine, Farnborough, England.

    Google Scholar 

  27. Cryssanthou, C., Kalberer, J., Jr., Kooperstein, S., and Antopol, W.: 1964, ‘Studies on Dysbarism. II: Influence of Bradykinin and “Bradykinin-Antagonists” on Decompression Sickness in Mice’, Aerospace Med. 35, 741–746.

    Google Scholar 

  28. Damato, M.J., Highly, F.M., Hendler, E., and Michel, E.L.: 1963, ‘Rapid Decompression Hazards After Prolonged Exposure to 50 Per Cent Oxygen - 50 Per Cent Nitrogen Atmosphere’, Aerospace Med. 34, 1037–1040.

    PubMed  CAS  Google Scholar 

  29. Damato, M. J., Kellett, G.L., and Coburn, K.R.: 1965, The Incidence of Aeroembolism Resulting from Rapid Decompression Following Exposure to a Mixed Gas Atmosphere at a Pressure of 380 mm Hg. NAEC-ACEL-529, U.S. Naval Air Engineering Center, Aerospace Crew Equipment Laboratory, Philadelphia, Pa.

    Google Scholar 

  30. Degner, E. A., Ikels, K.G., and Allen, T.H.: 1965, ‘Dissolved Nitrogen and Bends in Oxygen- Nitrogen Mixtures During Exercise at Decreased Pressures’, Aerospace Med. 36, 418–425.

    Google Scholar 

  31. Donnell, A. J., Jr. and Norton, C.P.: 1960, ‘Successful Use of the Recompression Chamber in Severe Decompression Sickness with Neurocirculatory Collapse: A Case Report’, Aerospace Med. 31, 1004–1009.

    Google Scholar 

  32. Downey, Y.M.: 1963, The Use of Overcompression in the Treatment of Decompression Sickness’, Aerospace Med. 34, 28–29.

    Google Scholar 

  33. Downey, V.M., Worley, T.W., Jr., Hackworth, R., and Whitley, J.L.: 1963, ‘Studies on Bubbles in Human Serum Under Increased and Decreased Atmospheric Pressures’, Aerospace Med. 34, 116–118.

    Google Scholar 

  34. Epstein, P. S. and Plesset, M. S.: 1950, ‘On the Stability of Gas Bubbles in Liquid-Gas Solutions’, J. Chem. Phys. 18, 1505–1509.

    Article  CAS  Google Scholar 

  35. Erde, A.: 1963, ‘Experience with Moderate Hypothermia in the Treatment of Nervous System Symptoms of Decompression Sickness’, in Proceedings of Second Symposium Underwater Physiology (ed. by C.J. Lambertson and L.J. Greenbaum, Jr.). NAS-NRC-1181, National Academy of Sciences - National Research Council, Washington, D.C., pp. 66–73.

    Google Scholar 

  36. Ferris, E.B., Jr. and Engel, G.L.: 1951, ‘The Clinical Nature of High Altitude Decompression Sickness’, in Decompression Sickness (ed. by J.G. Fulton ). W.B. Saunders Co., Philadelphia, pp. 4–52.

    Google Scholar 

  37. Ferris, E.B., Jr., Molle, W.E., Engel, G.L., and Brown, E.: 1944, Comparative Study of Decompression Sickness Under Varied Conditions of Exercise, Altitude and Denitrogenation. NAS-NRC-CAM-363, National Academy of Sciences — National Research Council, Committee on Aviation Medicine, Washington, D.C.

    Google Scholar 

  38. Flinn, D.E. and Womack, G.J.: 1963, ‘Neurological Manifestations of Dysbarism: A Review and Report of a Case with Multiple Episodes’, Aerospace Med. 34, 956–962.

    PubMed  CAS  Google Scholar 

  39. Fryer, D.I.: 1963, Decompression Sickness at 18500 feet: A Case History with Comment. FPRC/Memo 199, Flying Personnel Research Committee, Royal Air Force Institute of Aviation Medicine, Farnborough, England.

    Google Scholar 

  40. Goodman, M.W.: 1964, ‘Decompression Sickness Treated with Compression to 2–6 Atmospheres Absolute’, Aerospace Med. 35, 1204–1212.

    PubMed  CAS  Google Scholar 

  41. Gowdey, C. W. and Philp, R. B.: 1965, ‘Etiology and Treatment of Experimental Decompression Sickness with Special Reference to Body Lipids’, Milit. Med. 130, 648–652.

    CAS  Google Scholar 

  42. Gray, J. S.: 1951, ‘Constitutional Factors Affecting Susceptibility to Decompression Sickness’, in Decompression Sickness (ed. by J.G. Fulton ). W.B. Saunders Co., Philadelphia, pp. 182–191.

    Google Scholar 

  43. Gray, J.S.: 1944, Aeroembolism Induced by Exercise in Cadets at 23000 Feet. AF-SAM-227-1, U.S. Air Force Sch. Aviation Med., Randolph Field, Texas.

    Google Scholar 

  44. Gribble, M., De G.: 1960, ‘A Comparison of the “High-Altitude” and “High-Pressure” Syndromes of Decompression Sickness’, Brit. J. Industr. Med. 17, 181–186.

    PubMed  CAS  Google Scholar 

  45. Harris, R.I.: 1935, ‘Fat Embolism’, J.A.M.A. 105, 1013–1016.

    Google Scholar 

  46. Harvey, E.N.: 1965, ‘Decompression Sickness and Bubble Formation in Blood and Tissues’, Bull. N. Y. Acad. Med. 21, 505–536.

    Google Scholar 

  47. Haymaker, W. and Johnston, A.D.: 1965, ‘Pathology of Decompression Sickness: A Comparison of the Lesions in Airmen with Those in Caisson Workers and Divers’, Milit. Med. 117, 285–306.

    Google Scholar 

  48. Hetherington, A. W. and Miller, R. A.: 1946, ‘The Effect of Intravenous Nitrogen on the Respiration and Circulation of the Cat’, Fed. Proc. 5, 46.

    PubMed  CAS  Google Scholar 

  49. Henn, R.H.E. and Wünsche, O.: 1963, ‘Experimental Study of Fat Embolism’, in XI. European Aeronautical and Cosmonautical Medical Congress. DVL-273, Deutsche Versuchsanstalt für Luft- und Raumfahrt, E.V.

    Google Scholar 

  50. Henry, F.M.: 1953, Aviators’ “Bends” Pain as Influenced by Altitude and In-Flight Denitrogenation. WADC-TR-53-227, Wright Air Development Center, Wright-Patterson AFB, Ohio.

    Google Scholar 

  51. Henry, F.M.: 1956, ‘Effects of Exercise and Altitude on the Growth and Decay of Aviators’ Bends’, J. Aviat. Med. 27, 250–259.

    PubMed  CAS  Google Scholar 

  52. Henry, F.M., Cook, S.F., Stratman, E., and Lund, D.W.: 1944, Effectiveness of Preflight Oxygen Breathing in Preventing Decompression Sickness. NAS-NRC-CAM-384, National Academy of Sciences - National Research Council, Committee on Aviation Medicine, Washington, D.C.

    Google Scholar 

  53. Holmstrom, F. M.G. and Beyer, D.H.: 1965, Decompression Sickness and Its Medical Management: A Team Approach to the Study of Aviator’s Hemocirculatory Collapse. AF-SAM-TR-65- 21, U.S. Air Force Sch. Aerospace Med., Brooks AFB, Texas.

    Google Scholar 

  54. Hook, O.: 1958, ‘Dysbarism Manifested by Anterior Spinal Artery Syndrome: Further Report of a Case with Recovery’, J. Aviat. Med. 29, 540–543.

    PubMed  CAS  Google Scholar 

  55. Ivy, A.C., cited by Ferris, E.B. Jr. and Engel, G.L. (see ref. 36).

    Google Scholar 

  56. Jones, H.B.: 1950, ‘Respiratory System: Nitogen Elimination’, in Medical Physics (ed. by O. Glasser ). Year Book Publishers, Chicago, Vol. II, pp. 855–871.

    Google Scholar 

  57. Jones, H.B.: 1945, Preoxygenation and the Rate of Nitrogen Elimination with Regard to Decompression Sickness. NAS-NRC-CAM-491, National Academy of Sciences - National Research Council, Committee on Aviation Medicine, Washington, D.C.

    Google Scholar 

  58. Kellett, G.L., Coburn, K.R., and Hendler, E.: 1965, An Investigation of Decompression Hazards Following Equilibration in a Simulated Spacecraft Atmosphere of 50% O2-50% He at 380 mm Hg. NAEC-ACEL-540, U.S. Naval Air Engineering Center, Aerospace Crew Equipment Laboratory, Philadelphia, Pa.

    Google Scholar 

  59. Kern, J. D.: 1960, Etiology and Pathological Physiology of Decompression Sickness. NMRL- 345, U.S. Naval Medical Research Laboratory, New London, Conn.

    Google Scholar 

  60. Kindwall, E. P., Boreus, L.O., and Westerholm, B.: 1962, ‘Failure to Show Change in Rat Tissue Histamine and Serotonin After Rapid Decompression’, Amer. J. Physiol. 203, 389–390.

    PubMed  CAS  Google Scholar 

  61. Labout, H., Barthelemy, L., and Perrimond-Trouchet, R.: 1961, ‘Action de l’Héparine dans le Traitement des Accidents de Décompression’ [Action of Heparin in the Treatment of Decompression Accidents], Revue Agressologie 2, 229–236.

    Google Scholar 

  62. Lequire, V.S., Shapiro, J.L., and Lequire, C.B.: 1959, ‘A Study of the Pathogenesis of Fat Embolism Based on Human Necropsy Material and Animal Experiments’, Amer. J. Path. 35, 999–1015.

    PubMed  CAS  Google Scholar 

  63. Leverett, S.D., Bitter, H.L., and McIver, R.G.:1963, Studies in Decompression Sickness; Circulatory and Respiratory Changes Associated with Decompression Sickness in Anesthetized Dogs. AF-SAM-TDR-63-7, U.S. Air Force Sch. Aerospace Med., Brooks AFB, Texas.

    Google Scholar 

  64. Luft, U.C.: 1965, ‘Aviation Physiology - The Effets of Altitude’, in Handbook of Physiology, Section 3: Respiration, Vol II, American Physiological Society, Washington, D.C., pp. 1099–1145.

    Google Scholar 

  65. Malette, W.G., Fitzgerald, J.B., and Cockett, A.T.K.: 1961, Dysbarism: A Review of 35 Cases with Suggestion for Therapy. AF-SAM-Rev-3-61, U.S. Air Force Sch. Aviation Med., Brooks AFB, Texas.

    Google Scholar 

  66. Marbarger, T.P., Kemp, W.E., Kadetz, W., and Hansen, J.: 1958, ‘Studies in Aeroembolism’, J. Aviat. Med. 29, 291–300.

    PubMed  CAS  Google Scholar 

  67. Marotta, S.F., Marbarger, J. P., and Andersen, N.: 1961, ‘Incidence of Bends Following Partial Denitrogenation at Simulated Altitude’, Aerospace Med. 32, 289–295.

    PubMed  CAS  Google Scholar 

  68. Masland, R.L.: 1946, Injury of the Central Nervous System Resulting From Decompression to Simulated High Altitude. AF-SAM-481-1, U.S. Air Force Sch. Aviation Med., Randolph Field AFB, Texas.

    Google Scholar 

  69. Masland, R.L.: 1948, ‘Injury of the Central Nervous System Resulting From Decompression to Simulated High Altitudes’, Arch. Neurol. Psychiat. 59, 445–456.

    PubMed  CAS  Google Scholar 

  70. McIver, R.G.: 1963, ‘Medical Problems Encountered at High and Low Barometric Pressures’, Illinois Med. J. 123, 611–618.

    Google Scholar 

  71. McIver, R.G. and Kronenberg, R.S.: 1966, Treatment of Altitude Dysbarism with Oxygen Under High Pressure: Report of Three Cases, Presented at Fourth Internat. Biometeorological Congr., New Brunswick, N.J.

    Google Scholar 

  72. McIver, R. G. and Leverett, S. D., Jr.: 1963, Studies in Decompression Sickness: Cardiorespiratory Responses of Anesthetized Dogs to Compression Therapy Following Experimental Decompression Sickness. AF-SAM-TDR-63-94, U.S. Air Force Sch. Aerospace Med., Brooks AFB, Texas.

    Google Scholar 

  73. Murray, G.: 1960, ‘Fat Embolism and a Fat Center’, Amer. J. Surg. 100, 676–681.

    Article  PubMed  CAS  Google Scholar 

  74. National Aeronautics and Space Administration, Bioastronautics Data Book (ed. by P. Webb). NASA-SP-3006, National Aeronautics and Space Administration, Washington, D.C., 1964, p. 97.

    Google Scholar 

  75. Nims, L.F.: 1951, ‘Environmental Factors Affecting Decompression Sickness’, in Decompression Sickness (ed. by J.G. Fulton ). W.B. Saunders Co., Philadelphia, pp. 192–222.

    Google Scholar 

  76. Odland, L.T.: 1959, ‘Fatal Decompression Illness at an Altitude of 22000 Feet,’ Aerospace Med. 30, 840–846.

    PubMed  CAS  Google Scholar 

  77. Parsons, V.A.: 1958, ‘A Brief Review of Aviator’s Decompression Sickness and the High Altitude Selection Test’, J. Roy. Nav. Med. Serv. 44, 2–13.

    PubMed  CAS  Google Scholar 

  78. Peltier, L.F.: 1957, ‘An Appraisal of the Problem of Fat Embolism’, Int. Abstr. Surg. 104, 313–324.

    CAS  Google Scholar 

  79. Rait, W.L.: 1959, ‘The Etiology of Post-Decompression Shock in Aircrewmen’, Armed Forces Med. J. 10, 790–805.

    CAS  Google Scholar 

  80. Robie, R.R., Lovell, F. W., and Townsend, F. M.: 1960, ‘Pathological Findings in Three Cases of Decompression Sickness’, Aerospace Med. 31, 885–896.

    Google Scholar 

  81. Roth, E.M.: 1966, Space-Cabin Atmospheres. Part III. Physiological Factors of Inert Gases. NASA-SP-117, National Aeronautics and Space Administration, Washington, D.C.

    Google Scholar 

  82. Schneck, S.A.: 1957, ‘Decompression Sickness at Medium Altitude’, Armed Forces Med. J. 8, 1366–1370.

    CAS  Google Scholar 

  83. Thomas, S. and Williams, O.L.: 1944, High Altitude Joint Pains; Their Radiographic Aspects. NAS-NRC-CAM-395, National Academy of Sciences - National Research Council, Committee on Aviation Medicine, Washington, D.C.

    Google Scholar 

  84. Webb, J.P., Ferris, E.B., Engel, G.L., et al.: 1944, Radiographic Studies of the Knee During Bends. NAS-NRC-CAM-305, National Academy of Sciences - National Research Council, Committee on Aviation Medicine, Washington, D.C.

    Google Scholar 

  85. Weeth, J.B.: 1965, ‘Crippling Effects of Decompression Sickness: Report of Ten Cases’, Southern Med. J. 58, 657–660.

    Article  PubMed  CAS  Google Scholar 

  86. Whiteley, J. H.: 1954, ‘The Relation Between Tissue Injury and the Manifestations of Pulmonary Fat Embolism’, J. Path. Bact. 67, 521–530.

    Article  PubMed  CAS  Google Scholar 

  87. Whitten, R.H.: 1946, ‘Scotoma as a Complication of Decompression Sickness’, Arch. Ophthal. 36, 220–224.

    PubMed  CAS  Google Scholar 

  88. Wise, D. A.: 1963, Constitutional Factors in Decompression Sickness. NEDU-RR-2-63, U.S. Navy Experimental Diving Unit, Washington, D.C.

    Google Scholar 

  89. Wittmer, J.F.: 1962, Pathogenic Mechanisms in Gas and Fat Embolism. AF-SAM-Rev-4-62, U.S. Air Force Sch. Aerospace Med., Brooks AFB, Texas.

    Google Scholar 

  90. Womack, G.J.: 1961, ‘Evidence for the Cerebral Vasoconstrictor Effects of Breathing One Hundred Percent Oxygen, with Special Reference to the Treatment of Neurocirculatory Collapse as Seen in Cases of Dysbarism’, Aerospace Med. 32, 328–332.

    PubMed  CAS  Google Scholar 

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Busby, D.E. (1968). Decompression Sickness. In: Space Clinical Medicine. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-3464-7_4

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  • DOI: https://doi.org/10.1007/978-94-010-3464-7_4

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