The Mechanism and Control of the Biosynthesis of α-Lactalbumin by the Mammary Gland

Campbell, P. N.

doi:10.1007/978-94-010-2550-8_15

P. N. Campbell³

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Abstract

The mammary gland is potentially an excellent system for the study of the control of protein synthesis in eukaryotic cells. Not only can one study the way in which the synthesis of specific protein is switched on but also the events which occur at the cessation of milk secretion. The influence of hormones on these activities is important and for this purpose several excellent systems employing explants have been devised. Our aim has been to study the mechanism of control of protein synthesis at the level of the ribosome and for this purpose we have chosen to study the synthesis of a specific milk protein, namely α-lactalbumin (αLA), in extracts of guinea-pig mammary gland.

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References

Babad, H. and Hassid, W. Z. (1966). J. Biol. Chem. 241, 2672
PubMed CAS Google Scholar
Brodbeck, U., Denton, W. L., Tanahasi, N. and Ebner, K. E. (1967). J. Biol. Chem. 242, 1391
PubMed CAS Google Scholar
Brodbeck, U. and Ebner, K. E. (1966). J. Biol. Chem. 241, 762
PubMed CAS Google Scholar
Brew, K. (1969). Nature (London) 222, 671
Article CAS Google Scholar
Brew, K. and Campbell, P. N. (1967a). Biochem. J. 102, 258
PubMed CAS Google Scholar
Brew, K. and Campbell, P. N. (1967b). Biochem. J. 102, 265
PubMed CAS Google Scholar
Brew, K., Vanaman, T. C. and Hill, R. L. (1968). Proc. Nat. Acad. Sci., U.S., 59, 491
Article CAS Google Scholar
Fairhurst, E., Mcllreavy, D. and Campbell, P. N. (1971). Biochem. J. 123, 865
PubMed CAS Google Scholar
Falvey, A. K. and Staehelin, T. (1970). J. Mol Biol. 53, 21
Article PubMed CAS Google Scholar
Fraser, M. J. and Gutfreund, H. (1958). Proc. Roy. Soc. Ser. B. 149, 392
Article CAS Google Scholar
Gurdon, J. B., Lane, C. D., Woodland, H. R. and Marbaix, G. (1971). Nature (London) 233, 177
Article CAS Google Scholar
Hogan, B. L. M. and Korner, A. (1968). Biochim. Biophys. Acta. 169, 129
Article PubMed CAS Google Scholar
Lane, C. D., Marbaix, G. and Gurdon, J. B. (1971). J. Mol Biol. 61, 73
Article PubMed CAS Google Scholar
Lawford, G. R. (1969). Biochem. Biophys. Res. Commun. 37, 143
Article PubMed CAS Google Scholar
Mathews, M. B. and Korner, A. (1970). Eur. J. Biochem. 17, 328
Article PubMed CAS Google Scholar
Michael, S. E. (1961). Biochem. J. 82, 212
Google Scholar

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Authors and Affiliations

Department of Biochemistry, University of Leeds, England
P. N. Campbell

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P. N. Campbell
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Editors and Affiliations

Department of Histology and Embryology, University of Sydney, Sydney, Australia
J. K. Pollak
Wheat Research Unit, CSIRO, North Ryde, N.S.W., Australia
J. Wilson Lee

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Campbell, P.N. (1973). The Mechanism and Control of the Biosynthesis of α-Lactalbumin by the Mammary Gland. In: Pollak, J.K., Lee, J.W. (eds) The Biochemistry of Gene Expression in Higher Organisms. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-2550-8_15

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DOI: https://doi.org/10.1007/978-94-010-2550-8_15
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-2552-2
Online ISBN: 978-94-010-2550-8
eBook Packages: Springer Book Archive

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