Abstract
Since Carstensen and Schwan’s work on aqueous solutions of hemoglobin1 there have been a number of studies of excess acoustic absorption in solutions of biologically important macromolecules2–7 and their synthetic analogs8–10. Relaxation times or relaxation spectra adequate to characterize the observed frequency dependence of the ultrasonic velocity and attenuation have been deduced1–3,8,9 but the variety of chemical and structural equilibria possible in a solution of flexible polyelectrolytes is great enough to render the unambiguous identification of the microscopic process responsible for the excess absorption a matter of some difficulty. In individual cases arguments have been advanced nominating solvation1–3,8 ionization4,6, and conformational change5,9 as the principal contributors to the observed relaxation spectrum in aqueous protein solution.
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References
E.L. Carstensen and H.P. Schwan, J. Acoust. Soc. Amer., 31, 305 (1959).
F.W. Kremkau, E.L. Carstensen and W.G. Aldridge, ibid., 53, 1448 (1973).
(a) F. Schneider, F. Muller-Landau and A. Mayer, Biopolymers, 8, 537 (1969).
(b) P.D. Edmonds, Biochim. Biophys. Acta, 63, 216 (1962).
(c) M. Hussey and P.D. Edmonds, J. Phys. Chem., 75, 4012 (1971).
H. Inoue, J. Sci., Hiroshima Univ., A34, 37 (1970).
R. Zana and J. Lang, J. Phys. Chem., 74, 2735 (1970).
(a) F. Dunn and L.W. Kessler, J. Phys. Chem., 4, 2736 (1970).
(b) L.W. Kessler and F. Dunn, J. Phys. Chem., 73, 4256 (1969).
(c) W.D. O’Brien, Jr. and F. Dunn, J. Phys. Chem., 76, 528 (1972).
R.D. White and L.J. Slutsky, J. Col. Inter. Science, 37, 727 (1971).
Biopolymers, 11, 1973 (1972).
S.A. Hawley and F. Dunn, J. Chem. Phys., 50, 3523 (1969).
J. Burke, G. Hammes, and T. Levis, J. Chem. Phys., 42, 3520 (1965).
G.G. Hammes and P.N. Roberts, J. Am. Chem. Soc., 91, 1812 (1969).
(a1) R. Parker, L.J. Slutsky and J. Applegate, J. Phys. Chem. 72, 3177 (1968)
(a2) 70, 3018 (1966).
(b) A.D. Barksdale and J.E. Stuehr, J. Am. Chem. Soc. 94, 3337 (1972).
R. Zana and C. Tondre, Biopolymers, 10, 2635 (1971).
(a) M. Eigen and L. de Maeyer, “Technique of Organic Chemistry”, Vol. VIII, Part II, A. Weissberger, Jr., Ed., John Wiley and Sons, Inc. N.Y., 1961.
(b) H. Inoue, J. Sci. Hiroshima Univ., A34, 17 (1970).
(c1) D. Grimshaw, P.J. Heywood and E. Wyn-Jones, J.C.S., Faraday Soc. II, 69, 168 (1973)
(c2) ibid., 69, 756 (1973).
(d) S. Brun, J.E. Rassing and E. Wyn-Jones, Advances in Molecular Relaxation Processes, 5, 313 (1973).
M. Eigen and E. Eyring, J. Am. Chem. Soc., 84, 3254 (1962).
(a) K. Applegate, L.J. Slutsky and R.C. Parker, ibid., 90, 6909 (1968).
(b) R.D. White, L.J. Slutsky and S. Pattison, J. Phys. Chem. 75, 161 (1971).
R.D. White and W. Slutsky, J. Phys. Chem., 76, 1327 (1977).
E.J. Cohn and J.T. Edsall, Proteins, Amino Acids and Peptides as Ions and Dipolar Ions, Reinhold Publishing Corp., New York, 1943.
P. Debye, Trans. Electrochem. Soc., 82, 265 (1942).
M.V. Smoluchowski, Z. Physik. Chem. 92, 129 (1917).
W.H. Orttung, J. Am. Chem. Soc. 91, 162 (1969).
Biochem., 9, 2394 (1970).
C. Tanford and J.G. Kirkwood, J. Am. Chem. Soc., 79, 5333 (1957).
A. Elis, J. Chem. Soc., 1961, 4687.
S. Hamman and S. Lim, Austral. J. Chem., 1, 329 (1934).
G. Castellan, Ber, Bunsenges, Physik. Chem., 67, 898 (1963).
P.R. Schimmel, J. Chem. Phys., 54, 4136 (1971).
R.D. White (to be published).
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© 1975 D. Reidel Publishing Company, Dordrecht-Holland
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Slutsky, L.J., White, R.D. (1975). Ultrasonic Absorption in Protein Solution. In: Wyn-Jones, E. (eds) Chemical and Biological Applications of Relaxation Spectrometry. NATO Advanced Study Institutes Series, vol 18. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-1855-5_47
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DOI: https://doi.org/10.1007/978-94-010-1855-5_47
Publisher Name: Springer, Dordrecht
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