Abstract
Narcotic analgesics, typified by morphine, may be defined as central nervous system (CNS) depressants that relieve or abolish pain without, at the same time, inducing loss of consciousness. There is good evidence that they act at specific sites in the CNS. This class of drugs has diverse pharmacological action and side effects, the most undesirable of which are the development of tolerance and addiction involving both physical and psychological dependence on the drug, characteristics which seriously limit their clinical use as analgesics.
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© 1974 D. Reidel Publishing Company, Dordrecht-Holland
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Loew, G.H., Berkowitz, D., Weinstein, H., Srebrenik, S. (1974). Quantum Chemical Studies of Morphine-Like Opiate Narcotics: Effect of Polar Group Variations. In: Bergmann, E.D., Pullman, B. (eds) Molecular and Quantum Pharmacology. The Jerusalem Symposia on Quantum Chemistry and Biochemistry, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-1758-9_26
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DOI: https://doi.org/10.1007/978-94-010-1758-9_26
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