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Uncovering the Differences between T Cell Tolerance and Immunity

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Autoimmunity

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Abstract

In the last two decades, T cell function has been analyzed in vitro from many different angles, with a great deal of attention dedicated to the basic requirements of activation. During this time, a compendium of information has been collected and has proven to be invaluable. Paradoxically, very little is known about T cell activation and function in vivo. In the last decade, a number of models have been developed which allow the tracking of Ag-activated T cells in vivo and these studies have been instrumental in advancing the field of T cell biology. In particular, a new and emerging paradigm of T cell immunity is evolving.

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  1. Department of Microbiology, Oregon State University, Corvallis, Oregon, USA

    Anthony T. Vella

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  1. Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland

    Andrzej Górski , Hubert Krotkiewski  & Michał Zimecki ,  & 

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Vella, A.T. (2001). Uncovering the Differences between T Cell Tolerance and Immunity. In: Górski, A., Krotkiewski, H., Zimecki, M. (eds) Autoimmunity. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0981-2_2

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  • DOI: https://doi.org/10.1007/978-94-010-0981-2_2

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