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DARWINIZER® — a Computer Based Method for Peptide and Peptidomimetics Design

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Peptides: The Wave of the Future

Part of the book series: American Peptide Symposia ((APSY,volume 7))

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Abstract

Due to the metabolic instability of peptides, the design of modified isofunctional peptidomimetics is an adequate approach toward their application in pharmacology. DARWINIZER® is a computer-based tool for the de novo design of modified peptide structures. DARWINIZER® is an extension of the PepHarvester® and SME® algorithm [1–3] including non-canonical amino acids.

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Author information

Authors and Affiliations

  1. CallistoGen AG, Hennigsdorf, D-16761, Germany

    Matthias Filter & Paul Wrede

Authors
  1. Matthias Filter
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  2. Paul Wrede
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Editor information

Editors and Affiliations

  1. Spyder Instruments, Inc. and Illumina, Inc., 9885 Towne Centre Drive, 92121, San Diego, CA, USA

    Michal Lebl

  2. Torrey Pines Institute for Molecular Studies, Mixture Sciences, Inc., 3550 General Atomics Court, 92121, San Diego, CA, USA

    Richard A. Houghten

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© 2001 Springer Science+Business Media Dordrecht

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Filter, M., Wrede, P. (2001). DARWINIZER® — a Computer Based Method for Peptide and Peptidomimetics Design. In: Lebl, M., Houghten, R.A. (eds) Peptides: The Wave of the Future. American Peptide Symposia, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0464-0_199

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  • DOI: https://doi.org/10.1007/978-94-010-0464-0_199

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-3905-5

  • Online ISBN: 978-94-010-0464-0

  • eBook Packages: Springer Book Archive

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