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Structural Studies on the Yeast tRNAPhe by the 1H NMR of Modified Bases. Effect of Removal of the Y Base and Anticodon Binding

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Nuclear Magnetic Resonance Spectroscopy in Molecular Biology

Part of the book series: The Jerusalem Symposia on Quantum Chemistry and Biochemistry ((JSQC,volume 11))

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Abstract

Recent studies of Kan et al. [1] and Robillard et al. [2] monitoring the methyl and methylene resonances of yeast tRNAPhe in the high field region of the spectra have demonstrated that these resonances are very sensitive to structural changes which occur upon heating or chemical modification. Furthermore the assignment of these resonances is less ambiguous than is the assignment of H-bonded resonances. In this communication we report the assignments of the modified bases in yeast tRNAPhe at low temperature, and the effect of removal of the Y base from the anticodon loop of yeast tRNAPhe on the resonances of minor nucleosides.

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Author information

Authors and Affiliations

  1. Max-Planck-Institut für Experimentelle Medizin, D-3400, Göttingen, West Germany

    P. Davanloo-Malherbe, M. Sprinzl & F. Cramer

Authors
  1. P. Davanloo-Malherbe
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  2. M. Sprinzl
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  3. F. Cramer
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Editor information

Editors and Affiliations

  1. Institut de Biologie Physico-Chimique (Fondation Edmond de Rothschild), Université Pierre et Marie Curie (Paris VI), Paris, France

    Bernard Pullman

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© 1978 D. Reidel Publishing Company, Dordrecht, Holland

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Davanloo-Malherbe, P., Sprinzl, M., Cramer, F. (1978). Structural Studies on the Yeast tRNAPhe by the 1H NMR of Modified Bases. Effect of Removal of the Y Base and Anticodon Binding. In: Pullman, B. (eds) Nuclear Magnetic Resonance Spectroscopy in Molecular Biology. The Jerusalem Symposia on Quantum Chemistry and Biochemistry, vol 11. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-9882-7_10

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  • DOI: https://doi.org/10.1007/978-94-009-9882-7_10

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-9884-1

  • Online ISBN: 978-94-009-9882-7

  • eBook Packages: Springer Book Archive

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