A Technique for Non-Invasive His-Purkinje System (HPS) Recording
Electrocardiograms were recorded from human volunteers using bipolar chest electrodes and standard leads I, II and III. The chest lead signals were amplified approx. 105 times, filtered and time-averaged over 128 consecutive beats. For signal conditioning and averaging, an analog- and digital microprocessor-based system was employed. The noise reduction resulting from the averaging technique permitted extraction of microvolt-range activity in the P-Q segment of the heart cycle otherwise regarded as silent. The recorded waveforms were triangular, approx. 5 msec in duration and 3-6 microvolts in amplitude. They preceded the ventricular depolarization complexes by 25–45 msec. On some volunteer patients, the externally-recorded waveform was compared with an internal electrogram recorded from an indwelling catheter. The correlation of events corresponding with internally-recorded His bundle activity was promising.
KeywordsRecorded Waveform Microprocessor System Consecutive Beat Bundle Activity Heart Rhythm Disturbance
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