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Limitations in Measurement of Prostaglandins and Thromboxanes

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Part of the book series: Developments in Pharmacology ((DIPH,volume 1))

Abstract

The development of quantitative methods, sensitive and specific enough for the measurement of the extremely small physiological amounts of prostaglandins and related compounds, has always constituted a great problem for researchers in the field. Published quantitative data display very wide discrepancies, even in studies of similar design. For example, reported “basal levels” of certain prostaglandins in peripheral plasma range from only 1 or 2 pg/ml to several ng/ml (1–6). Various sources of error probably contribute greatly to many of these results.

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© 1980 ECSC, EEC, EAEC, Brussels-Luxembourg

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Kindahl, H., Granström, E. (1980). Limitations in Measurement of Prostaglandins and Thromboxanes. In: Boeynaems, J.M., Herman, A.G. (eds) Prostaglandins, Prostacyclin, and Thromboxanes Measurement. Developments in Pharmacology, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8916-0_1

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  • DOI: https://doi.org/10.1007/978-94-009-8916-0_1

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-8918-4

  • Online ISBN: 978-94-009-8916-0

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