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Interference with Spermatozoa Capacitation

  • Chapter
Regulation of Male Fertility

Part of the book series: Clinics in Andrology ((CLAN,volume 5))

Abstract

Even though some developed nations are concerned about negative population growth values, more adequate contraceptive techniques to control the world-wide population explosion persists as one of our more important needs. The urgency of the search for new contraceptives has, if anything, increased in the last decade in view of:

  1. 1)

    The growing concern about possible adverse effects of the long-term use of the pill.

  2. 2)

    The high number of women abandoning the use of intrauterine devices.

  3. 3)

    The low number of women using long-term progestagens or the morning after pill.

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References

  • Aketa K, (1975) Physiological studies on the sperm surface component responsible for sperm-egg binding in sea urchin fertilization. II. Effect of Concanavalin A on the fertilizing capacity of sperm. Exp Cell Res 90: 56.

    Article  PubMed  CAS  Google Scholar 

  • Austin CR, (1951) Observations on the penetration of the sperm into the mammalian egg. Aust J biol Sci [B] 4: 581.

    CAS  Google Scholar 

  • Bedford JM, (1970) Sperm capacitation and fertilization in mammals. Biol Reprod 2 [Suppl]: 128.

    Article  PubMed  CAS  Google Scholar 

  • Blank M, Soo L, Britten JS, (1976) Adsorption of albumin on rabbit sperm membranes. J Membr Biol 29: 401.

    Article  PubMed  CAS  Google Scholar 

  • Bleau G, Vandenheuvel WJA, Andersen OF, Gwatkin RBL, (1975) Desmosteryl sulphate of hamster spermatozoa, a potent inhibitor of capacitation in vitro. J Reprod Fertil 43: 175.

    Article  PubMed  CAS  Google Scholar 

  • Briggs MH, (1973) Steroid hormones and fertilizing capacity of spermatozoa. Steroids 22: 547.

    Article  PubMed  CAS  Google Scholar 

  • Briggs MH, Briggs M, (1976) Biochemical contraception. Prospects for human development. London: Academic.

    Google Scholar 

  • Chang MC (1951) Fertilizing capacity of spermatozoa deposited into the fallopian tubes. Nature 168: 697.

    Article  PubMed  CAS  Google Scholar 

  • Chang MC, Austin CR, Bedford JM, Brackett BG, Hunter RHF, Yanagimachi R, (1977) Capacitation of spermatozoa and fertilization in mammals. In: Greep RO, Koblinsky MA, (eds) Frontiers in reproduction and fertility control. MIT Press, p 434.

    Google Scholar 

  • Davis BK (1971) Macromolecular inhibitor of fertilization in rabbit seminal plasma. Proc Natl Acad Sci USA 68: 951.

    Article  PubMed  CAS  Google Scholar 

  • Davis BK, (1976) Influence of serum albumin on the fertilizing ability in vitro of rat spermatozoa. Proc Soc Exp biol Med 151: 240.

    PubMed  CAS  Google Scholar 

  • Davis BK, Hungund BJ, (1976) Effect of modified membrane vesicles from seminal plasma on the fertilizing capacity of rabbit spermatozoa. Biochem Biophys Res Commun 69: 1004.

    Article  PubMed  CAS  Google Scholar 

  • Delgado NM, Huacuja L, Pancardo RM, Merchant H, Rosado A, (1976) Changes in the protein conformation of human spermatozoal membranes after treatment with cyclic adenosine B’-S’-monophosphate and human follicular fluid. Fértil Steril 27: 413.

    PubMed  CAS  Google Scholar 

  • Durr R, Shur B, Roth S, (1977) Sperm-associated syalyl transferase activity. Nature 265: 547.

    Article  PubMed  CAS  Google Scholar 

  • Eng LA, Oliphant G, (1978) Rabbit sperm reversible decapacitation by membrane stabilization with a highly purified glycoprotein from seminal plasma. Biol Reprod 19: 1083.

    Article  PubMed  CAS  Google Scholar 

  • Ericsson RJ, Buthala DA, Norland JF, (1971) Fertilization of rabbit ova in vitro by sperm with adsorbed Sendai virus. Science 173: 54.

    Article  PubMed  CAS  Google Scholar 

  • Friend DS, Orci L, Perrlet A, Yanagimachi R, (1977) Membrane particle changes attending the acrosome reaction in guinea pig spermatozoa. J Cell Biol 74: 561.

    Article  PubMed  CAS  Google Scholar 

  • Gordon M, Dandekar PV, Bartoszewicz W, (1975) The surface coat of epididymal ejaculated and capacitated sperm. J Ultrastruct Res 50: 199.

    Article  PubMed  CAS  Google Scholar 

  • Gwatkin RBL, Andersen OF, (1973) Effect of glycosidase inhibitors on the capacitation of hamster spermatozoa by cumulus cells in vitro. J Reprod Fértil 35: 565.

    Article  PubMed  CAS  Google Scholar 

  • Gwatkin RBL, Williams DT, (1970) Inhibition of sperm capacitation in vitro by contraceptive steroids. Nature 227: 182.

    Article  PubMed  CAS  Google Scholar 

  • Hartree EF, (1975) The acrosome-lysosome relationship. J Reprod Fértil 44: 125.

    Article  PubMed  CAS  Google Scholar 

  • Hernández O, Ballesteros LM, Rosado A, (1979) Binding of 17- beta-estradiol to the outer surface and nucleus of human spermatozoa. Arch Androl 3: 23.

    Article  Google Scholar 

  • Hernández-Jáuregui P, Sosa A, González-Angulo A, Rosado A, (1975) The glycocalyx in human spermatozoa: a cytochemical study In: Hess M, (ed) Electron microscopic concepts of secretion. Ultrastructure of endocrinal and reproductive organs. New York: John Wiley and Sons, p 223.

    Google Scholar 

  • Hicks JJ, Rosado A, (1974) Steroid hormones and spermatozoa metabolism. In: Briggs MH, (ed) Advances in steroid bio-chemistry and pharmacology. Vol 5. London: Academic, p 263.

    Google Scholar 

  • Hicks JJ, Martinez-Manautou J. Pedrón N. Rosado A. (1972a) Metabolic changes in human spermatozoa related to capa-citation. Fértil Steril 23: 172.

    PubMed  CAS  Google Scholar 

  • Hicks JJ, Pedrón N, Rosado A, (1972b) Modifications of human spermatozoa glycolysis by cyclic adenosine monophosphate (cAMP), estrogens and follicular fluid. Fértil Steril 23: 886.

    PubMed  CAS  Google Scholar 

  • Hoskins DD, Casillas ER, (1975) Function of cyclic nucleotides in mammalian spermatozoa. In: Greep RO, Astwood EB, (eds) Handbook of physiology, Sect 7: Endocrinology, Vol 5: Male reproductive system. Washington. D.C., American Physiological Society, p 453.

    Google Scholar 

  • Huacuja L, Delgado NM, Merchant H, Pancardo RM, Rosado A, (1977) Cyclic AMP induced incorporation of 33 Pi into human spermatozoa membrane components. Biol Reprod 17: 89.

    Article  PubMed  CAS  Google Scholar 

  • Jecht EW, Bernstein GS, (1973) The influence of copper on the motility of human spermatozoa. Contraception 7: 381.

    Article  CAS  Google Scholar 

  • Johnson MH, (1975) The macromolecular organization of membranes and its bearing on events leading up to fertilization. J Reprod Fértil 44: 167.

    Article  PubMed  CAS  Google Scholar 

  • Kinsey WH, Koehler JK, (1978) Cell surface changes associated with in vitro capacitation of hamster sperm. J Ultrastruct Res 64: 1.

    Article  PubMed  CAS  Google Scholar 

  • Koehler JK, Gaddum-Rosse P, (1975) Media induced alterations of the membrane associated particles of the guinea pig sperm tail. J Ultrastruct Res 51: 106.

    Article  PubMed  CAS  Google Scholar 

  • Lacko L, Wittke B, Lacko I, (1977) The pH and temperature dependence of the interaction of steroid hormones with the transport systems of glucose in human erythrocytes. J Cell Physiol 90: 161.

    Article  PubMed  CAS  Google Scholar 

  • Lewis BK, Ketchel MM. (1972) Effects of female reproductive tract secretions on rabbit sperm. II. Control of sperm hyaluronidase release. Proc Soc Exp Biol Med 141: 719.

    PubMed  CAS  Google Scholar 

  • Mercado E, Rosado A. (1973) Structural properties of the membrane of intact human spermatozoa. A study with fluorescent probes. Biochim Biophys Acta 298: 639.

    Google Scholar 

  • Mercado E. Carvajal G, Reyes A, Rosado A, (1976) Sulfhydryl groups on the spermatozoa membrane. A study with a new fluorescent probe for SH groups. Biol Reprod 14: 632.

    Article  PubMed  CAS  Google Scholar 

  • Mercado E. Aznar R, Gallegos AJ, Dominguez R, Rosado A, (1977) Subcellular distribution of lysosomal enzymes in the human endometrium. II. Effect of the inert and copper and progesterone-releasing T intrauterine devices. Contraception 16: 299.

    Article  CAS  Google Scholar 

  • Nicolson GL, Yanagimachi R, (1974) Mobility and the restric-tion of mobility of plasma membrane lectin-binding components. Science 184: 1294.

    Article  PubMed  CAS  Google Scholar 

  • Pedron N, Hicks JJ. Lara-Ricalde R, Rosado A, (1973) Effect of some contraceptive steroids upon the human spermatozoa. Contraception 7: 213.

    Article  CAS  Google Scholar 

  • Reyes A, Oliphant G. Brackett BG, (1975a) Partial purification and identification of a reversible decapacitation factor from rabbit seminal plasma. Fertil Steril 26: 148.

    PubMed  CAS  Google Scholar 

  • Reyes A. Mercado E. Rosado A, (1975b) Inhibition of capacitation and of the fertilizing capacity of rabbit spermatozoa by blocking membrane sulfhydryl groups. In: Campos da Paz A, Drill VA, Hayashi M, Rodriguez W, Schally AV, (eds) Recent advance in human reproduction. Amsterdam: Excerpta Medica, p 322.

    Google Scholar 

  • Reyes A, Mercado E, Goicoechea B, Rosado A. (1976) Partici-pation of membrane sulfhydryl groups in the epididymal maturation of human and rabbit spermatozoa. Fertil Steril 27: 1452.

    PubMed  CAS  Google Scholar 

  • Reyes A. Goicoechea B, Rosado A. (1978) Calcium ion requirement for rabbit spermatozoal capacitation and enhancement of fertilizing ability by ionophore A23187 and cyclic adenosine 3-5’- monophosphate. Fertil Steril 29: 451.

    CAS  Google Scholar 

  • Rosado A, Hicks JJ, Martinez-Zedillo G, Bondani A, Martinez- Manautou J, (1970) Inhibition of human sperm motility by calcium and zinc ions. Contraception 2: 259.

    Article  CAS  Google Scholar 

  • Rosado A, Velazquez A. Lara-Ricalde R, (1973) Cell polarography. II. Effect of neuraminidase and follicular fluid upon the surface characteristics of human spermatozoa. Fertil Steril 24: 349.

    Google Scholar 

  • Rosado A, Hicks JJ, Reyes A, Blanco I. (1974a) Capacitation in vitro of rabbit spermatozoa with cyclic adenosine mono-phosphate and human follicular fluid. Fertil Steril 25: 821.

    PubMed  CAS  Google Scholar 

  • Rosado A, Hicks J J, Aznar R, Mercado E, (1974b) Intrauterine contraception with the progesterone-T device. Interference with the metabolic activity and capacitation of spermatozoa. Contraception 9: 39.

    Google Scholar 

  • Rosado A, Huacuja L, Delgado NM, Hicks JJ, Pancardo RM, (1975) Cyclic-AMP receptors in the human spermatozoa membrane. Life Sci 17: 1707.

    Article  PubMed  CAS  Google Scholar 

  • Rudy B, Gitler C, (1972) Microviscosity of the cell membranes. Biochim Biophys Acta 288: 231.

    Article  PubMed  CAS  Google Scholar 

  • Salhany JM, Swanson JC, Cordes KA, Gaines SB, Gaines KC, (1978) Evidence suggesting direct oxidation of human ery-throcyte membrane sulfhydryls by copper. Biochem Biophys Res Commun 82: 1294.

    Article  PubMed  CAS  Google Scholar 

  • Singer SJ, (1974) On the fluidity and asymmetry of biological membranes. In: Estrada-OS, Gitler C. (eds) Perspectives in membrane biology. New York: Academic, p 131.

    Google Scholar 

  • Srivastava PN, Gould KG, (1973) Inhibition of the fertilizing capacity of rabbit spermatozoa by sialoproteins. Contraception 7: 65.

    Article  CAS  Google Scholar 

  • Stambaugh R, Smith M, (1978) Tubulin and microtubule-like structures in mammalian acrosomes. J Exp Zool 203: 135.

    Article  PubMed  CAS  Google Scholar 

  • Szego CM, (1974) The lysosome as a mediator of hormone action. Recent Prog Horm Res 30: 171.

    PubMed  CAS  Google Scholar 

  • Weissmann G, Goldstein I, Hoffstein S, Chauvet G, Robineaux R, (1975) Ying/yang modulation of lysosomal enzyme release from polymorphonuclear leukocytes by cyclic nucleotides. Ann NY Acad Sci 256: 222.

    Article  PubMed  CAS  Google Scholar 

  • Yanagimachi R, Usui N, (1974) Calcium dependence of the acrosome reaction and activation of guinea pig spermatozoa. Exp Cell Res 89: 161.

    Article  PubMed  CAS  Google Scholar 

  • Zaneveld LJD, (1976) Sperm enzyme inhibitors as antifertility agents. In: Hafez ESE, (ed) Human semen and fertility regulation in men. St Louis: CV Mosby, p 570.

    Google Scholar 

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© 1980 Martinus Nijhoff Publishers bv. The Hague/Boston/London

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Reyes, A., Chavarria, M.E., Rosado, A. (1980). Interference with Spermatozoa Capacitation. In: Cunningham, G.R., Schill, WB., Hafez, E.S.E. (eds) Regulation of Male Fertility. Clinics in Andrology, vol 5. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8875-0_14

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  • DOI: https://doi.org/10.1007/978-94-009-8875-0_14

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-8877-4

  • Online ISBN: 978-94-009-8875-0

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