Clinical Applications of Cell Kinetics to Chemotherapy of Human Malignancy

  • Alvin M. Mauer
Part of the Developments in Oncology book series (DION, volume 2)


During the past two decades, we have learned a great deal about the characteristics of cell growth in human malignancy. A most important contribution to the study of cell population kinetics was the introduction of the label tritiated thymidine which, for the first time, allowed for the identification of cells in DNA synthesis by autoradiography. Furthermore, in situations where serial samples of the tissue under study could be obtained, it was possible to follow the initially labeled population of DNA synthesizing cells through the subsequent phases of the cell cycle.


Proliferative Activity Acute Leukemia Cytosine Arabinoside Growth Fraction Nitrogen Mustard 
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Copyright information

© Martinus Nijhoff Publishers bv, The Hague 1980

Authors and Affiliations

  • Alvin M. Mauer
    • 1
  1. 1.St. Jude Children’s Research HospitalMemphisUSA

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