Abstract
Myocardial perfusion depends upon the pressure and is a function of the resistance of the coronary vessels. The resistance changes with the diameter of the vessels and with the number of flow-limiting vascular structures. A restriction of coronary flow may be caused by “autoregulation” which causes changes in the width of the resistance vessels, controlled by a feedback mechanism, according to the metabolic demand of the myocardium. In addition myocardial contraction causes a decrease of flow within the intramural coronary branches during systole by extravascular compression. Such an increase and decrease of coronary arterial and also coronary venous flow during the cardiac cycle has been experimentally confirmed by previous investigations (1,2,3,4). With these observations evidence was brought forward that coronary resistance is composed of a vascular and an extravascular component.
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© 1980 Martinus Nijhoff Publishers bv, The Hague, Boston, London
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Wüsten, B., Schaper, W. (1980). Quantification of Extravascular Coronary Resistance. In: Baan, J., Arntzenius, A.C., Yellin, E.L. (eds) Cardiac Dynamics. Developments in Cardiovascular Medicine, vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8796-8_24
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DOI: https://doi.org/10.1007/978-94-009-8796-8_24
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