Origin and Structure of the Osteoclast

  • J. L. E. Ericsson
  • Dorothy F. Bainton
  • Elisabeth Ch. M. Hoefsmit


The existence of multinucleated giant cells — as distinguished from megakaryocytes — in bone has been known since the middle of the nineteenth century. Kölliker (1873) thought that these cells might represent the ‘agents of bone résorption’ and gave them the name of ‘osteoclasts’.


Acid Phosphatase Brush Border Cacodylate Buffer Mononuclear Phagocyte Multinucleated Giant Cell 
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Copyright information

© Springer Science+Business Media Dordrecht 1980

Authors and Affiliations

  • J. L. E. Ericsson
  • Dorothy F. Bainton
  • Elisabeth Ch. M. Hoefsmit

There are no affiliations available

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