Controlled/Critical Tests in the Evaluation of Anthelmintic Activity

Abstract

Registration authorities and consumers are justified in demanding extensive information on veterinary drugs: this includes the spectrum of activity, pharmacological data, residues and tolerance/toxicity. These data can be obtained only in animal studies, and studies should be so designed that the minimum number is used. Thus, an internationally agreed standard for test methods could be a prerequisite for the registration authorities of various countries. The first symposium of the ‘World Association for the Advancement of Veterinary Parasitology’ was held in Hannover in 1963, under the title, ‘Evaluation of Anthelmintics’. Since then, efforts to standardise the methods of laboratory and field evaluation of anthelmintics have continued.