Treatment of Cattle Nematodiasis with ®Panacur

  • D. Düwel
Part of the Current Topics in Veterinary Medicine and Animal Science book series (CTVM, volume 9)


The data on investigations with fenbendazole (FBZ) a vermifugal anthelminthic are summarised. FBZ is well tolerated up to 267 – 400 times the oral therapeutic does of 5 – 7.5 mg/kg. Pharmacokinetic data demonstrate a short half-life for the compound in serum and milk; residues in tissues are extremely small. The mode of action has been demonstrated to be a combination of a disorder of the energy metabolism and neurotoxis effects.

The spectrum of activity of FBZ covers practically all the economically important nematodes of the gastro-intestinal tract and lungs of cattle; FBZ is effective against both adult and immature nematodes including the inhibited stages of Ostertagia and other nematodes. In addition, it has an ovicidal and larvicidal activity. The weightgains and the increase in milk output which result after FBZ treatment emphasise the advantage of treatment with FBZ.


Milk Output Larvicidal Activity Carcase Weight Faecal Culture Housing Period 
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Copyright information

© ECSC, EEC, EAEC, Brussels-Luxembourg 1981

Authors and Affiliations

  • D. Düwel
    • 1
  1. 1.Hoechst AG, HelminthologieFrankfurt/M. 80Federal Republic of Germany

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