Advertisement

Antibiotic Treatment of Chronic Bronchitis

  • R. J. Davies
  • G. K. Knowles
Part of the New Perspectives in Clinical Microbiology book series (NPCM, volume 4)

Abstract

Chronic bronchitis remains a major cause of disability in the middle aged and elderly and is responsible for approximately 20000 deaths each year in the United Kingdom. Despite the importance of cigarette smoking in the aetiology of this disease, environmental and social factors are also of consequence. Indeed recent information suggests that both disability and death from chronic bronchitis are decreasing in the U.K. possibly as a result of the clean air policy which has dramatically reduced the level of atmospheric pollution [1]. The prevalence of chronic bronchitis varies greatly in different countries independent of cigarette smoking, and between rural and urban areas [2]. However, in one recent study of over 12 000 individuals aged between 45 and 70 years old in South East London, symptoms of chronic bronchitis were reported in 15% [3].

Keywords

Force Vital Capacity Acute Exacerbation Chronic Bronchitis Haemophilus Influenzae Airflow Obstruction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Howard P: The changing face of chronic bronchitis with airways obstruction. Br Med J 2: 89, 1974.PubMedCrossRefGoogle Scholar
  2. 2.
    Reid DD: The international background to studies of chronic non-specific lung disease in children. In: Bronchitis III (Orie NGM Van der Leude R eds), Royal Van Gorcum, Assen, 1970.Google Scholar
  3. 3.
    D’Souza MF, Davies RJ, Swan AV: Factors associated with reported asthma in middle age. 1980, in press.Google Scholar
  4. 4.
    Medical Research Council: Definition and classification of chronic bronchitis for clinical and epidemiological purposes. Lancet 1: 775, 1965.Google Scholar
  5. 5.
    Fisher M, Akhtar AJ, Calder MA, Moffat AJ, Stewart SM, Sealley H, Crofton JW: Pilot study of factors associated with exacerbations in chronic bronchitis. Br Med J 4: 187, 1969.PubMedCrossRefGoogle Scholar
  6. 6.
    Lambert HP, Stern M: Infective factors in exacerbations of bronchitis and asthma. Br Med J 3: 323, 1972.PubMedCrossRefGoogle Scholar
  7. 7.
    Gump DW, Phillips CA, Forsyth BR, McIntosh K, Lamborn KR and Stouch WH: Role of infection in chronic bronchitis. Am Rev Respir Dis 113: 465, 1976.PubMedGoogle Scholar
  8. 8.
    Gregg I: The role of viral infection in asthma and bronchitis. Royal College of Physicians of Edinburgh. Publication No. 46, 1975.Google Scholar
  9. 9.
    May JR: The bacteriology of chronic bronchitis. Lancet, 2: 534, 1953.Google Scholar
  10. 10.
    Lees AW, McNaught W: Bacteriology of lower respiratory tract secretions, sputum and upper respiratory tract secretions in `normals’ and chronic bronchitis. Lancet 2: 1112, 1959.PubMedCrossRefGoogle Scholar
  11. 11.
    Laurenzi GA, Potter RT, Kass EH: Bacteriologic flora of the lower respiratory tract. N Engl J Med 265: 1273, 1961.PubMedCrossRefGoogle Scholar
  12. 12.
    Burns MW, May JR: Haemophilus influenzae precipitins in the serum of patients with chronic bronchial disorders. Lancet 1: 354, 1967.PubMedCrossRefGoogle Scholar
  13. 13.
    Miller DL, Jones R: The bacterial flora of the upper respiratory tract and sputum of working men. J Path Bact 87: 182, 1964.PubMedCrossRefGoogle Scholar
  14. 14.
    Tagar I, Speizer FE: Role of infection in chronic bronchitis. N Engl J Med 292: 563, 1975.CrossRefGoogle Scholar
  15. 15.
    Pines A, Raafat H, Greenfield JSB, Linsell WD, Solari ME: Antibiotic regimens in moderately ill patients with purulent exacerbations of chronic bronchitis. Br J Dis Chest 66: 107, 1972.PubMedCrossRefGoogle Scholar
  16. 16.
    Francis RS, May JR, Spicer CC: Chemotherapy of bronchitis. Br Med J 2: 979, 1961.PubMedCrossRefGoogle Scholar
  17. 17.
    Medical Research Council: Value of chemoprophylaxis and chemotherapy in early chronic bronchitis. Brit Med J 1: 1317, 1966.CrossRefGoogle Scholar
  18. 18.
    May JR, Delves DM: Ampicillin in the treatment of Haemophilus influenzae infections of the respiratory tract. Thorax 19: 298, 1964.PubMedCrossRefGoogle Scholar
  19. 19.
    Hughes, DTD: Single-blind comparative trial of trimethoprin-sulphamethoxazole and ampicillin in the treatment of exacerbations of chronic bronchitis. Br Med J 4: 470, 1969.PubMedCrossRefGoogle Scholar
  20. 20.
    Pines A, Raafat H, Greenfield JSB, Marshall MJ, Solari M: Penicillin, ampicillin and cephaloridine in severe exacerbations of purulent bronchitis in elderly patients. Br J Dis Chest 65: 91, 1971.PubMedCrossRefGoogle Scholar
  21. 21.
    May JR, Ingold A: Amoxycillin in the treatment of chronic non-tuberculous bronchial infections. Br J Dis Chest 66: 185, 1972.PubMedCrossRefGoogle Scholar
  22. 22.
    Willey RF, Gould JC, Grant IWB: A comparison of ampicillin, erythromycin and erythromycin with sulphamctopyrazine in the treatment of infective exacerbations of chronic bronchitis. Br J Dis Chest 72: 13, 1978.PubMedCrossRefGoogle Scholar
  23. 23.
    Davies RJ: Skin tests and total IgE levels in reported asthma in middle age. Clin. Allergy 9: 417, 1979.CrossRefGoogle Scholar
  24. 24.
    Cotes JE: Lung Function Assessment and Application in Medicine, Blackwell Scientific Publications, Oxford, 1975, p. 386.Google Scholar
  25. 25.
    May JR, May DS: Bacteriology of sputum in chronic bronchitis. Tubercle (London), 44: 162, 1963.CrossRefGoogle Scholar
  26. 26.
    Rawlins GA: Liquefaction of sputum for bacteriological examination. Lancet 2: 538, 1953.CrossRefGoogle Scholar
  27. 27.
    Rawlins GA: Cytological examination of sputum in relation to its macroscopic purulence. J Clin Path 8: 114, 1965.CrossRefGoogle Scholar
  28. 28.
    Roberts DE, Cole P: Effect of tobacco and nicotine on growth of Haemophilus influenzae in vitro. J Clin Path 32: 728, 1979.PubMedCrossRefGoogle Scholar
  29. 29.
    Oswald NC, Harold JT, Martin WJ: Clinical patterns of chronic bronchitis. Lancet 2: 639, 1953.CrossRefGoogle Scholar
  30. 30.
    Reid RD, Fairburn AS: The natural history of chronic bronchitis. Lancet 1: 1147, 1958.PubMedCrossRefGoogle Scholar
  31. 31.
    May JR, Peto R, Tinker CM, Fletcher CM: A study of Haemophilus influenzae precipitins in the serum of working men in relation to smoking habits, bronchial infection and airway obstruction. Am Rev Respir Dis 108: 460, 1973.PubMedGoogle Scholar
  32. 32.
    Fletcher CM, Peto R, Speizer FS, Tinker CM: A follow-up study of the natural history of obstructive bronchitis. In: Bronchitis III ( Orie NGM, Van der Lende R, eds.), Royal Vangorcum, Assen, 1970, p. 103.Google Scholar
  33. 33.
    Howard P: A long term follow up of respiratory symptoms and ventilatory function in a group of working men. Br J Ind Med 27: 326, 1970.PubMedGoogle Scholar
  34. 34.
    Fletcher CM, Peto R, Tinker C, Speizer FE: The Natural History of Chronic Bronchitis and Emphysema. Oxford University Press, Oxford, 1976.Google Scholar

Copyright information

© Martinus Nijhoff Publishers, The Hague 1981

Authors and Affiliations

  • R. J. Davies
  • G. K. Knowles

There are no affiliations available

Personalised recommendations