Adaptation of 24-Hour Hormonal Patterns and Sleep to Jet Lag
Effects of rapid transmeridian time shifts on behavioral and biological parameters such as vigilance, heart rate, and urinary excretion of electrolytes and corticosteroids have been demonstrated (1, 2, 3). Because of the key role played by hormones in the adaptation to the environment, disruptions in the temporal organization of hormonal secretion might be involved in the production of the jet lag syndrome. The current availability of sensitive hormone assays has made it possible to test this hypothesis. Moreover, assessment of jet lag induced changes of the 24-h hormonal profiles and their pattern of adaptation is expected to bring further insight into the control of the various hormonal rhythms, the identity of their zeitgebers and their possible interrelationships.
KeywordsTotal Plasma Protein Cortisol Peak Disruption Score Melatonin Rhythm Hormonal Pattern
Unable to display preview. Download preview PDF.
- 4.Desir, D, E Van Cauter, J Golstein, VS Fang, E Martino, C Jadot, JP Spire, P Noël, S Refetoff, and G Copinschi, Effects of jet lag on hormonal patterns. I. Procedures, variations in total plasma proteins and disruption of ACTH-cortisol periodicity. J Clin Endocrinol Metab in press, 1981Google Scholar
- 5.Fevre-Montange, M, E Van Cauter, S Refetoff, D Desir, J Tourniaire, and G Copinschi, Effects of jet lag on hormonal patterns. II. Adaptation of melatonin circadian periodicity. J Clin Endocrinol Metab in press, 1981Google Scholar
- 6.Badawi, M, S Bila, M L’Hermite, FR Perez-Lopez, and C Robyn, Comparative evaluation of radioimmunoassay methods for human prolactin using anti-ovine and anti-human prolactin sera, In: Radioimmunoassay and Related Procedures in Medicine, International Atomic Energy Agency, Wien, vol. 1, 411–422, 1974Google Scholar
- 7.Rechtschaffen, A, and A Kales, A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects. Publich Health Service, Government Printing Office, Washington, D.C., 1968Google Scholar
- 10.Van Cauter, E, Method for the characterization of 24-hour temporal variations of blood components. Am J Physiol 6: E255 - E264, 1979Google Scholar
- 12.Krieger, DT and J Aschoff, Endocrine and other Biological rhythms, In: Endocrinology, DeGroot LJ (ed.), New York, Grune and Stratton, vol. ii, p. 2079, 1979Google Scholar