Abstract
The adequacy of quality control is a basic tennant of any research endeavor. The definition of antiarrhythmic drug efficacy is based on quantitative data obtained by long-term electrocardiographic recordings. Three important elements of the quality control of such monitoring data include: 1) the adequacy of the recording instruments and the analyzer, 2) the quality of the data tape itself, and 3) the accuracy and repeatability of the analysis method. Quality control of the recorder and the analysis system requires careful attention to several technical components to ensure adequate recorder speed, frequency response of the instruments, synchronization of the ECG stylus, and linearity of the amplifiers. The data tape itself must be carefully scrutinized to determine that proper electrode application was performed to avoid excessive motion artifact and to ensure that the recorder was not faulty and that the battery had adequate power.
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© 1981 Martinus Nijhojf Publishers bv, The Hague.
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Morganroth, J. (1981). Long-Term Ambulatory Electrocardiographic Recording in the Determination of Efficacy of New Antiarrhythmic Agents. In: Morganroth, J., Moore, E.N., Dreifus, L.S., Michelson, E.L. (eds) The Evaluation of New Antiarrhythmic Drugs. Developments in Cardiovascular Medicine, vol 11. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8270-3_8
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DOI: https://doi.org/10.1007/978-94-009-8270-3_8
Publisher Name: Springer, Dordrecht
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