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Orotic Acid pp 23–25Cite as

Alterations in Orotic Acid Excretion

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Abstract

Enhanced excretion of orotic acid was observed under different physiological [209,210] and nutritional [211–217] conditions. The amount of orotic acid excreted during human pregnancy is about 20–40 mg per day and does not vary substantially during the course of pregnancy [209,210]. Inherited deficiencies of the urea cycle [218], purine nucleoside Phosphorylase [219], and especially of orotate phosphoribosyltransferase and orotidylic acid decarboxylase also result in an increased excretion of orotic acid.

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Authors and Affiliations

  1. Institute of Organic Chemistry and Biochemistry, Czechoslovakia Academy of Sciences Prague, Czechoslovakia

    Alois Čihák PhD

  2. Institut für Molekularbiologie und Biochemie der Freien Universität, Berlin, Germany

    Werner Reutter MD

Authors
  1. Alois Čihák PhD
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  2. Werner Reutter MD
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© 1980 A. Čihák and W. Reutter

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Čihák, A., Reutter, W. (1980). Alterations in Orotic Acid Excretion. In: Orotic Acid. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8043-3_5

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  • DOI: https://doi.org/10.1007/978-94-009-8043-3_5

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-8045-7

  • Online ISBN: 978-94-009-8043-3

  • eBook Packages: Springer Book Archive

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