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Platelet Therapy

  • Chapter
Bloodtransfusion and Problems of Bleeding

Part of the book series: Developments in Hematology and Immunology ((DIHI,volume 5))

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Abstract

In the twenty or so years since platelets first became available in a highly concentrated form for transfusion to thrombocytopenic patients, platelet therapy has established itself as an integral and vital component in the management of such patients. Dramatic changes in medical practice, and the full-fledged development of medical oncology as a separate discipline, owe much to the expanding blood component technology which has provided them with highly concentrated preparations of viable and hemostatically competent platelets. Surgery, trauma, chemotherapy and radiotherapy have, as well, all been altered by the ready availability of platelet concentrates. Whereas in the 1960s, over 75% of deaths in acute leukemia were the result of hemorrhage directly attributable to thrombocytopenia (37), this figure has been radically lowered to no more than 10% to 20%, at this time. Chemotherapy and radiotherapy continue to push to the limits of bone marrow tolerance, and surgery is undertaken in thrombocytopenic patients formerly considered inoperable.

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  1. A. J. Silvergleid
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Editors and Affiliations

  1. Red Cross Bloodbank Groningen-Drenthe, Groningen, The Netherlands

    P. C. Das

  2. Central Laboratory of the Dutch, Red Cross, Amsterdam, The Netherlands

    J. J. van Loghem (Professor of Immunology) (Professor of Immunology)

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© 1982 Martinus Nijhoff Publishers, The Hague

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Silvergleid, A.J. (1982). Platelet Therapy. In: Smit Sibinga, C.T., Das, P.C., van Loghem, J.J. (eds) Bloodtransfusion and Problems of Bleeding. Developments in Hematology and Immunology, vol 5. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-7692-4_7

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