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Role of Obesity in the Pathogenesis of Primary Hypertension

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Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 16))

Abstract

In the past, the obese have been considered to be of jovial and easy-going character. Yet, they seem to pay heavily for these social qualities as far as their physical health is concerned. Obesity was dismissed as a contributor to disease [1], due to the lack of a direct cause-and-effect relationship and because the association of obesity with disease was largely epidemiological. In this context, Mann[l] distinguishes between causation and association, and claims that obesity is an inevitable and incurable condition, at least in western society. He maintains that treatment is so ineffective that its influence on any disease process cannot be evaluated. Berger[2], in his review at the 3rd International Congress on Obesity, claimed that the higher mortality rates in obesity were only associated with an overweight which exceeded the ideal body weight by at least 25–30%. Van Itallie, however, found that even 10% over the ideal weight was associated with higher mortality rates [3]. He compared mortality rates according to variations in body weight in three separate studies: the Build and Blood Pressure Study [4], The American Cancer Society Study [5] and the Build Study [4]. From their tables it can be seen that at 10% overweight, the mortality percentage is 113, 107 and 111 respectively for males and 109, 108 and 107 respectively for females. At 30% overweight these figures increase to 142, 137 and 135 respectively for males and 130, 138 and 125 respectively for females.

He is fat and scant of breath. Hamlet, V, 2, 298.

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© 1982 Martinus Nijhoff Publishers, The Hague

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Eliahou, H.E. (1982). Role of Obesity in the Pathogenesis of Primary Hypertension. In: Amery, A., Fagard, R., Lijnen, P., Staessen, J. (eds) Hypertensive Cardiovascular Disease: Pathophysiology and Treatment. Developments in Cardiovascular Medicine, vol 16. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-7476-0_17

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  • DOI: https://doi.org/10.1007/978-94-009-7476-0_17

  • Publisher Name: Springer, Dordrecht

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