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Postmortem: Anatomic Quantitation

  • Chapter
Myocardial Infarction

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 14))

Abstract

Anatomic estimation of infarct size is considered to be the standard against which other methods of estimating infarct size should be tested. In most animal studies, evaluation of techniques for estimating infarct size as well as evaluation of interventions for limiting infarct size are based upon the direct anatomic determination of infarct size as a benchmark. Clinical studies using direct anatomic estimation of infarct size are less common because, fortunately, relatively few hospitalized patients die after an infarct. Moreover, the small percentage of patients in clinical studies who are autopsied may not be representative of the entire study population, since large or complicated infarcts are probably more common in this group than in the general population of patients with infarcts. Although a larger percentage of patients with small infarcts could be studied by obtaining needle biopsies of the left ventricle during cardiac surgery [1], such studies would not enable accurate estimation of infarct size because of the limited amount of tissue sampled.

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Authors
  1. Raymond E. Ideker
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  2. Donald B. Hackel
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  3. Eric C. McClees
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Editor information

Editors and Affiliations

  1. Duke University Medical Center, Durham, North Carolina, USA

    Galen S. Wagner M.D.

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© 1982 Martinus Nijhoff Publishers, The Hague / Boston / London

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Ideker, R.E., Hackel, D.B., McClees, E.C. (1982). Postmortem: Anatomic Quantitation. In: Wagner, G.S. (eds) Myocardial Infarction. Developments in Cardiovascular Medicine, vol 14. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-7452-4_14

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  • DOI: https://doi.org/10.1007/978-94-009-7452-4_14

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-7454-8

  • Online ISBN: 978-94-009-7452-4

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