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Treatment related leukemia

  • Chapter
Adult Leukemias 1

Part of the book series: Cancer Treatment and Research ((CTAR,volume 5))

Abstract

The literature is replete with reports of the putative relationship of aggressive treatment of malignant, and even benign, disease and the development of acute myelogenous leukemia. Do these reports reflect an increased risk of developing acute leukemia? If so, is this simply a part of the natural history of the primary neoplasm, or benign disease, which is more recently becoming manifest because of improvement in treatment and concomitant improvement in survival? On the other hand, is this risk of leukemia due to the more aggressive treatment programs themselves? The characteristic clinical picture and the refractory nature of the leukemia which occurs in the setting is clearly different from the spontaneous acute leukemia seen in otherwise normal patients and makes unlikely the alternative possibility of spontaneous leukemia occurring in long term survivors.

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Authors
  1. Charles A. Coltman Jr.
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  1. University of Minnesota, Minneapolis, USA

    Clara D. Bloomfield

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© 1982 Martinus Nijhoff Publishers bv, The Hague

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Coltman, C.A. (1982). Treatment related leukemia. In: Bloomfield, C.D. (eds) Adult Leukemias 1. Cancer Treatment and Research, vol 5. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-7433-3_3

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  • DOI: https://doi.org/10.1007/978-94-009-7433-3_3

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