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Transport and Inherited Disease pp 71–84Cite as

Some regulatory principles in epithelial transport

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Abstract

This symposium takes place as I am about to leave the Max-Planck-Institute for Biophysics after 13 years of stimulating and rewarding research. Looking through the work done during this period by myself and in collaboration with my colleagues, it becomes evident that almost all of the studies have been linked, more or less closely, to the question of regulatory principles in epithelial transport. In rereading these papers, it is interesting to note how they reflect the change in emphasis that was placed for a long time on the metabolic events occurring in the intracellular compartment to the emphasis that is placed nowadays on the events occurring at the barrier between the extra- and intracellular compartment, the cell membrane. Therefore in this chapter I would like to develop, taking my own work as guideline, some general aspects of regulation of transport. This is not intended to be a complete review; its main intent is to provide a framework of concepts concerning the basic principles of epithelial transport and the sites and selectivity of its regulation that might be useful for studies of transport phenomena in health and disease.

Dedicated to Prof. Dr K. J. Ullrich in deep appreciation of his generous support and scientific and personal advice.

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References

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Authors
  1. R. Kinne
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Editor information

Editors and Affiliations

  1. Department of Child Life and Health, University of Edinburgh, 17, Hatton Place, Edinburgh, UK

    N. R. Belton

  2. Department of Chemical Pathology, Old Medical School, Thoresby Place, Leeds, UK

    C. Toothill

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© 1981 The Society for the Study of Inborn Errors of Metabolism

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Kinne, R. (1981). Some regulatory principles in epithelial transport. In: Belton, N.R., Toothill, C. (eds) Transport and Inherited Disease. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-7316-9_4

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  • DOI: https://doi.org/10.1007/978-94-009-7316-9_4

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-7318-3

  • Online ISBN: 978-94-009-7316-9

  • eBook Packages: Springer Book Archive

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