Abstract
DNA synthesis was inhibited during embryogenesis of Habrotrocha rosa with mitomycin C and hydroxyurea. Inhibition of DNA replication in early stages of embryogenesis, at the beginning of organogenesis, just after cavitation of the stomodeum, resulted in a complete inhibition of further development. After this stage of embryogenesis development was insensitive to inhibition of DNA replication.
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References
Kersten, H. & Kersten, W., 1974. Inhibitors of nucleic acid synthesis. Springer Verlag, Heidelberg - London - New York.
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Plasota, K. & Plasota, M., 1980. Some problems in the embryogenesis of Habrotrocha rosa Donner 1949. Hydrobiologia 70: 39–41.
Sinclair, W.K., 1965. Hydroxyurea: Differential lethal effects on cultured mammalian cells during the cell cycle. Science 150: 1729–1731.
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© 1983 Dr W. Junk Publishers, The Hague
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Plasota, K., Plasota, M., Kunicki-Goldfinger, W.J.H. (1983). Macromolecular synthesis during embryogenesis of Habrotrocha rosa Donner I. Replication of DNA. In: Pejler, B., Starkweather, R., Nogrady, T. (eds) Biology of Rotifers. Developments in Hydrobiology, vol 14. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-7287-2_17
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DOI: https://doi.org/10.1007/978-94-009-7287-2_17
Publisher Name: Springer, Dordrecht
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