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Clinical Studies of the Abdomen: Scintigraphic and Other Techniques in the Management of Patients with Abdominal Disease

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Diagnostic Imaging in Medicine

Part of the book series: NATO ASI Series ((NSSE,volume 61))

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Abstract

Abdominal diseases are among the most frequent ailments which specialists in diagnostic imaging must examine. Imaging procedures, in order to be used most effectively, should complement the history, physical examination, and other laboratory tests in order to achieve the most accurate, rapid, and cost efficient diagnosis. The choice of diagnostic procedures currently available is greater than ever before. The selection of appropriate studies and the order in which they are performed may have a profound effect on diagnostic accuracy and clinical success. This chapter will deal primarily with scintigraphy of the abdomen as it relates to esophageal disorders, liver-spleen scintigraphy, gastroesophageal reflux, gastric emptying studies, hepatobiliary scintigraphy, and gastrointestinal bleeding studies, including the detection of Meckel’s diverticulum.

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References

  1. Griffith, G.H., G.M. Owen, S. Kirkman, and R. Shields. “Measurement of rate of gastric emptying using Chromium-51.” Lancet 1 (1966) 1244-1245.

    Article  PubMed  CAS  Google Scholar 

  2. Harvey, R.F., N.J.G. Brown, D.B. Mackie, D.H. Keeling, and W.T. Davies. “Measurement of gastric emptying time with a gamma camera.” Lancet 1 (1970) 16-18.

    Article  PubMed  CAS  Google Scholar 

  3. Jones, T., J.C. Clark, N. Kocak, A.G. Cox and H.I. Glass. “Measurement of gastric emptying using the scintillation camera and Cs-129.” Brit J Radiology 43 (1979) 537-541.

    Article  Google Scholar 

  4. Meyer, J.H., M.B. MacGregor, R. Gueller, P. Martin, and R. Cavalieri. “Tc-99m-tagged chicken liver as a marker of solid food in the human stomach.” Digestive Dis 21 (1976) 296-304.

    Article  CAS  Google Scholar 

  5. Harvey, E., M. Loberg, and M. Cooper. “Tc-99m-HIDA. A new radiopharmaceutical for hepatobiliary imaging.” J Nucl Med 16 (1975) 533.

    Google Scholar 

  6. Fisher, R.S. et al. “Gastroesophageal (GE) scintiscan-a new method to detect and quantitate GE reflux.” Gastroenterology 70 (1976) 301.

    PubMed  CAS  Google Scholar 

  7. Malmud, L.S. “Radionuclide studies of gastric emptying and enterogastric reflux.” In Peptic Ulcer Diseases -- An Update. Third International Symposium on Gastroenterology (March 18-24, 1979), New York, Biomedical Information Corporation, 1979.

    Google Scholar 

  8. Malmud, L.S., and R.S. Fisher. “Quantitation of gastroesophageal reflux before and after therapy using the gastroesophageal scintiscan.” South Med J 71 Suppl 1 (1978) 10.

    PubMed  Google Scholar 

  9. Tolin, R.D., et al. “Enterogastric reflux in normal subjects and patients with Bilroth II gastroenterostomy” Gastroenterology 77 (1979) 1027.

    PubMed  CAS  Google Scholar 

  10. Tolin, R.D., et al. “Esophageal scintigraphy to quantitate esophageal transit.” Gastroenterology 76 (1979) 1402.

    PubMed  CAS  Google Scholar 

  11. Weinstein, W.M., E.R. Bogach and K.L. Bowes. “The normal human esophageal mucosa: a histological reappraisal.” Gastroenterology 68 (1975) 40-44.

    PubMed  CAS  Google Scholar 

  12. Fisher, R.S. et al. “The lower esophageal sphincter as a barrier to gastroesophageal reflux.” Gastroenterology 72 (1977) 19.

    PubMed  CAS  Google Scholar 

  13. Stelzer, F., et al. “Abnormal gallbladder emptying in patients with gallstones or vagotomy and Bilroth II gastroenterostomy.” Clin Res 27 (1979) 272.

    Google Scholar 

  14. Skucas, J., and W.W. Schrank. “The routine air-contrast examination of the esophagus.” Radiology 115 (1975) 482-484.

    PubMed  CAS  Google Scholar 

  15. Margulis, A.R. “Water-soluble radiographic contrast agents in the gastrointestinal tract.” In Radiographic Contrast Agents. R.E. Miller and J. Skucas, Eds., (University Park Press, Baltimore, 1977) p. 188.

    Google Scholar 

  16. Sandmark, S. “Hiatal incompetence.” Acta Radiol Supplement 219 (1963).

    Google Scholar 

  17. Bernstein, I.M., and I.A. Baker. “A clinical test for esophagitis.” Gastroenterology 34 (1958) 760-781.

    PubMed  CAS  Google Scholar 

  18. Battle, W.S., L.M. Nyhus and C.T. Bombeck. “Gastroesophageal reflux: diagnosis and treatment.” Ann Surg 177 (1973) 560-564.

    Article  PubMed  CAS  Google Scholar 

  19. Donner, M.W., et al. “Acid barium swallows in the radiographic evaluation of clinical esophagitis.” Radiology 87 (1966) 220.

    PubMed  CAS  Google Scholar 

  20. Hookman, P., et al. “Acid induced esophageal motor abnormalities. A cine-manometric study.” Gastroenterology 48 (1965) 822.

    Google Scholar 

  21. Calderon, M., R.E. Sonnemaker, T. Hersh, J.A. Burdine. “Tc-99m human albumin microspheres (HAM) for measuring the rate of gastric emptying.” Radiology 101 (1971) 371-374.

    PubMed  CAS  Google Scholar 

  22. Malmud, L.S., and R.S. Fisher. “Scintigraphic evaluation of disorders of the duodenum, esophagus and stomach.” Med Clinics N Amer. (1981) in press.

    Google Scholar 

  23. Paull, A., J.S. Trier, M.D. Dalton, R.C. Camp, P. Loeb, and R.K. Goyal. “The histologic spectrum of Barrett’s esophagus.” N Engl J Med 295 (1976) 476-480.

    Article  PubMed  CAS  Google Scholar 

  24. Berquist, T.H., N.G. Nolan, H.C. Carlson and D.H. Stephens. “Diagnosis of Barrett’s esophagus by pertechnetate scintigraphy.” Mayo Clin Proc 48 (1973) 276-279.

    PubMed  CAS  Google Scholar 

  25. Fisher, R.S., et al. “Anti-reflux surgery for symptomatic gastric esophageal reflux: mechanism of action.” Am J Dig Dis 23 (1978) 152.

    Article  PubMed  CAS  Google Scholar 

  26. Texter, E.C. “Fluorocinematography.” Curr Gastroenterol 9 (1961) 983-1001.

    Google Scholar 

  27. Wolf, B.S. and M.T. Khilnani. “Progress in gastrointestinal radiology.” Gastroenterology 51 (1966) 542-559.

    PubMed  CAS  Google Scholar 

  28. Ismail-Beigi, F., P.F. Horton, and CF. Pope. “Histological consequences of gastroesophageal reflux in man.” Gastroenterology 58 (1970) 163-174.

    PubMed  CAS  Google Scholar 

  29. Kobayashi, S. and T. Kasugai. “Endoscopic and biopsy criteria for the diagnosis of esophagitis with a fiberoptic eso-phagoscope.” Am J Dig Dis 19 (1974) 345-352.

    Article  PubMed  CAS  Google Scholar 

  30. Pope, CE. “A dynamic test of sphicter strength: its application to the lower esophageal sphincter.” Gastroenterology 52 (1967) 779-786.

    PubMed  Google Scholar 

  31. Winans, C.S. and L.D. Harris. “Quantitation of lower esophageal sphincter competence.” Gastroenterology 52 (1967) 773-778.

    PubMed  CAS  Google Scholar 

  32. Conway, J.J., et al. “Radionuclide evaluation of gastroesophageal reflux in children.” J Nucl Med 20 (1979) 680.

    Google Scholar 

  33. Heyman, S., et al. “The radionuclide detection of gastroesophageal reflux and aspiration in children.” J Nucl Med 20 (1979) 680.

    Google Scholar 

  34. Bushkin, F.L., et al. “Post-operative alkaline reflux gastrititis.” Surg Gyn Obst 138 (1972) 933-938.

    Google Scholar 

  35. Duplessis, D.J. “Alkaline reflux gastritis.” S Afr Med J 42 (1968) 134-136.

    Google Scholar 

  36. Mackman, S., K. Lemmer and J. Morrissey. “Post-operative gastritis and esophagitis.” Amer J Surg 121 (1971) 694-697.

    Article  PubMed  CAS  Google Scholar 

  37. Scudamore, “Bile reflux gastritis.” Amer J Gast 60 (1973) 9-22.

    CAS  Google Scholar 

  38. Toye, D. and J. Williams. “Post-gastrectomy bile vomiting.” Lancet 2 (1965) 524-526.

    Article  PubMed  CAS  Google Scholar 

  39. Capper, W.M. “Factors in the pathogenesis of gastric ulcer.” Ann Roy Coll Surg Eng 40 (1967) 21-35.

    PubMed  CAS  Google Scholar 

  40. Delaney, J.P., J.W.B. Cheng, and B.A. Butler, et. al. “Gastric ulcer and regurgitation gastritis.” Gut 11 (1970) 715-719.

    Article  PubMed  CAS  Google Scholar 

  41. Duplessis, D.J. “Pathogenesis of gastric ulceration.” Lancet 1 (1965) 974-978.

    Article  PubMed  CAS  Google Scholar 

  42. Fisher, R.S. and S. Cohen. “Pyloric sphincter dysfunction in patients with gastric ulcer.” New Engl J Med 288 (1973) 273-276.

    Article  PubMed  CAS  Google Scholar 

  43. Rhodes, J., D.E. Barnardo, and S.F. Phillips, et al. “Increased reflux of bile into the stomach in patients with gastric ulcer.” Gastroenterology 57 (1969) 241-252.

    PubMed  CAS  Google Scholar 

  44. Gillison, A. “The significance of bile in reflux esophagitis.” Surg Gyn Obst 134 (1972) 419-424.

    PubMed  CAS  Google Scholar 

  45. Kaye, M.D. and P. Showalter. “Pyloric incompetence in reflux esophagitis.” Clin Res 20 (1972) 733.

    Google Scholar 

  46. Moffat, R.C. and E.M. Berkas. “Bile esophagitis.” Arch Surg 91 (1965) 963-966.

    PubMed  CAS  Google Scholar 

  47. Windsor, C.W.D. “Gastroesophageal reflux after partial gastrectomy.” Brit Med J 2 (1967) 1233-1234.

    Article  Google Scholar 

  48. Johnson, A.G. “Pyloric function and gallstone dyspepsia.” Brit J Surg 50 (1972) 450-454.

    Google Scholar 

  49. Capper, W.M., Buckler, T.J. and J.V. Kilby, et al. “Gallstones, gastric secretion and flatulent dyspepsia.” Lancet 1 (1967) 413-415.

    Article  PubMed  CAS  Google Scholar 

  50. Snedecor, G.W. and W.C. Cochran. “Statistical Methods.” Sixth Edition, Ames, Iowa State University Press, 1967.

    Google Scholar 

  51. Beaumont, W. “Experiments and observations on the gastric juice and the physiology of digestion.” Plattsburg, Allen, 1833.

    Google Scholar 

  52. Hunt, J.N. and W.R. Spurrell. “The pattern of emptying of the human stomach.” J Physiol (London) 113 (1951) 157-168.

    CAS  Google Scholar 

  53. George, J.D. “New clinical method for measuring the rate of gastric emptying: The double sampling test method.” Gut 9 (1968) 237-242.

    Article  PubMed  CAS  Google Scholar 

  54. Malagelada, J.R., G.F. Longstreth, W.H.J. Summerskill and V.L.W. Go. “Measurement of gastric functions during digestion of ordinary solid meals in man.” Gastroenterology 70 (1976) 203-210.

    PubMed  CAS  Google Scholar 

  55. Malagelada, J.R. “Quantification of gastric solid-liquid discrimination during digestion of ordinary meals.” Gastroenterology 72 (1977) 1265-1267.

    Google Scholar 

  56. Fordtran, J.S., and J.H. Walsh. “Gastric acid secretion rate and buffer content of the stomach after eating: Results in normal subjects and in patients with duodenal ulcer.” J Clin Invest 52 (1973) 645-657.

    Article  PubMed  CAS  Google Scholar 

  57. Horton, R.E., F.G.M. Ross and G.H. Darling. “Determination of the emptying-time of the stomach by use of enteric coated barium granules.” Brit Med J 1 (1965) 1537-1539.

    Article  PubMed  CAS  Google Scholar 

  58. Pendergrass, E.P., I.S. Ravdin, CG. Johnston and P.J. Hodes. “Studies of the small intestine. II The effect of food and various pathologic states on gastric emptying and the small intestinal pattern.” Radiology 26 (1936) 651-662.

    Google Scholar 

  59. Heading, R.C., P. Tothill, CP. McLoughlin and D.J.C. Shearman. “Gastric emptying rate measurement in man: A double isotope scanning technique for simultaneous study of liquid and solid components of a meal.” Gastroenterology 71 (1976) 45-50.

    PubMed  CAS  Google Scholar 

  60. Benmair, Y., F. Dreyfuss, B. Fishel, E.H. Frei and G. Gilat. “Study of gastric emptying using a ferro-magnetic tracer.” Gastroenterology 73 (1977) 1041-1045.

    PubMed  CAS  Google Scholar 

  61. Fordtran, J.S. “Acid secretion in paptic ulcer.” In Gastrointestinal Disease. M.H. Sleisenger, J.S. Fordtran, eds. W.B. Saunders Co., Philadelphia, pp 174-188, 1973.

    Google Scholar 

  62. Scarpello, J.H.B., D.C Barber, R.V. Hague, D.R. Cullen, and G.E. Sladen. “Gastric emptying of solid meals in diabetes.” Brit Med J 2 (1976) 671-673.

    Article  PubMed  CAS  Google Scholar 

  63. Griffith, G.H., C.M. Owen, H. Campbell, and R. Shields. “Gastric emptying in health and in gastroduodenal disease” Gastroenterology 54 (1968) 1-7.

    PubMed  CAS  Google Scholar 

  64. Malagelada, J.R., G.F. Longstreth, T.B. Deering, W.H.J. Summerskill, and V.L.W. Go. “Gastric secretion and empty- ing after ordinary meals in duodenal ulcer.” Gastroenterology 73 (1977) 989-994.

    PubMed  CAS  Google Scholar 

  65. Chaudhuri, T.K. “Use of Tc-99m-DTPA for measuring gastric emptying time.” J Nuclear Med 15 (1974) 319-395.

    Google Scholar 

  66. Code, C.F. and H.C. Carlson. “Motor activity of the stomach.” In. Handbook of Physiology, Section 6, Alimentary Canal, Vol. IV, CF Code, eds., American Physiological Society, Washington, DC, pp 1903-1916, 1968.

    Google Scholar 

  67. Carlson, H.C, CF. Code, and R.A. Nelson. “Motor activity of the canine gastroduodenal junction: A cineadiographic, pressure, and electric study.” Amer J Digestive Dis 11 (1966) 155-172.

    Article  CAS  Google Scholar 

  68. Bass, P., CF. Code and E.H. Lambert. “Electrical activity of the gastroduodenal junction.” Amer J Physiol 201 (1961) 587-592.

    PubMed  CAS  Google Scholar 

  69. Cannon, W.B., and C.W. Lieb. “The receptive relaxation of the stomach.” Amer J Physiol 29 (1911) 267-273.

    Google Scholar 

  70. Hunt, J.N. and I. McDonald. “The influence of volume on gastric emptying.” J Physiol (London) 126 (1954) 459-474.

    CAS  Google Scholar 

  71. Kwong, N.J., B.H. Brown, CE. Whittaker, and H. E. Duthie. “Effect of gastrin I, secretin, and cholecystokinin-pancreozimin on the electrical activity, motor activity, and acid output of the stomach in man.” Scand J Gastroenterology 7 (1972) 161-170.

    CAS  Google Scholar 

  72. Thomas, J.E. “Mechanisms and regulation of gastric emptying.” Physol Rev 37 (1957) 435-474.

    Google Scholar 

  73. Hunt, J.N. “The duodenal regulation of gastric emptying.” Gastroentrology 45 (1963) 149-156.

    CAS  Google Scholar 

  74. Sheiner, H.J. “Progress Report: Gastric emptying tests in man.” Gut 16 (1975) 235-247.

    Article  PubMed  CAS  Google Scholar 

  75. Hunt, J.N. and W.R. Spurrell. “The pattern of emptying of the human stomach.” J Physiol (London) 113 (1951) 157-168.

    CAS  Google Scholar 

  76. George, J.D. “Gastric acidity and motility.” Amer J Digestive Dis 13 (1968) 376-383.

    Article  CAS  Google Scholar 

  77. Meeroff, J.C., V.L.W. Go, and S.F. Phillips. “Gastric emptying of liquids in man: Quantification by duodenal recovery marker.” Mayo Clinic Proc 48 (1973) 728-732.

    CAS  Google Scholar 

  78. Sun, D.C.H., H. Shay, and H.J. Woloshin. “Effect of tricyclamol on gastric emptying and intestinal transit.” Amer J Digestive Dis 4 (1959) 282-288.

    Article  CAS  Google Scholar 

  79. Hopkins, A. “The patterns of gastric emptying: A new view of old results.” J Physiol (London) 182 (1966) 144-149.

    CAS  Google Scholar 

  80. Clarke, R.J. and J. Allexander-Williams. “The effect of preserving antral innervation and of a pyloroplasty on gastric emptying after vagotomy in man. Gut 14 (1973) 300-307.

    Article  PubMed  CAS  Google Scholar 

  81. Cobb, J.S., S. Bank, I.N. Marks, and J.H. Louw. “Gastric emptying after vagotomy and pyloroplasty.” Amer J Digestive Dis 16 (1971) 207-215.

    Article  CAS  Google Scholar 

  82. Aylett, P., C. Wastell, and I. Wise. “Gastric secretion and emptying before and after vagotomy and pyloroplasty, with and without continuous infusion of pentagastrin.” Amer J Digestive Dis 14 (1969) 256-252.

    Google Scholar 

  83. McKelvey, S.T.D. “Gastric incontinence and post-vago-tomy diarrhea.” Brit J Surgery 57 (1970) 741-747.

    Article  CAS  Google Scholar 

  84. Smalley, R.V., Malmud, L.S. and W.G.M. Ritchie. “Preoperative scanning: Evaluation for metastatic disease in carcinoma of the breast, lung, colon, bladder and prostate.” Semin in Oncology 7 (1980) 358-369.

    CAS  Google Scholar 

  85. Eikman, E.A., J.L. Cameron, M. Coleman, T.K. Natarajan, P. Dugal, and H.N. Wagner Jr. “A test for patency of the cystic duct in acute cholecystitis.” Ann Int Med 82 (1975) 318-322.

    PubMed  CAS  Google Scholar 

  86. Weissman, H.S., M.S. Frank, L.H. Bernstein, and L.M. Freeman. “Rapid and accurate diagnosis of acute cholecystitis with Tc-99m-HIDA cholescintigraphy.” Am J Roentgen 132 (1979) 523-528.

    Google Scholar 

  87. Rosenthall, L., E.A. Shaffer, and R. Lisbona, et al. “Diagnosis of hepatobiliary disease by Tc-99m-HIDA cholescintigraphy.” Radiology 126 (1978) 467-474.

    PubMed  CAS  Google Scholar 

  88. Rosenthall, L., C. Fonseca, A. Arzoumanian, M. Hernandez, and D. Greenberg. “Tc-99m-HIDA hepatobiliary imaging following upper abdominal surgery.” Radiology 130 (1979) 735-739.

    PubMed  CAS  Google Scholar 

  89. Alavi, A., R.W. Dann, S. Baum, and D.N. Biery. “Scintigraphic detection of acute gastrointestinal bleeding.” Radiology 124 (1977) 753-756.

    PubMed  CAS  Google Scholar 

  90. Winzelberg, G.G., K.A. McKusick, H.W. Strauss, A.C. Waltman, and A.J. Greenfield. “Evaluation of Gastrointestinal bleeding by red blood cells labeled in vivo with Tc-99m.” J Nucl Med 20 (1979) 1080-1086.

    PubMed  CAS  Google Scholar 

  91. Winzelberg, G.G., J.W. Froelich, K.A. McKusick, A.C. Waltman, A.J. Greenfield, and H.W. Strauss. “Radionuclide localization of lower gastrointestinal hemorrhage.” Radiology 139 (1981) 465-469.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Nuclear Medicine, Temple University School of Medicine, 19140, Philadelphia, PA, USA

    Leon S. Malmud M.D. (Professor and Chairman)

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  1. Leon S. Malmud M.D.
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Editors and Affiliations

  1. Division of Nuclear Medicine, George Washington University Medical Center, 901 Twenty-Third Street, N.W. Washington DC, 20037, USA

    Richard C. Reba M.D. (Professor of Radiology and Medicine Director) (Professor of Radiology and Medicine Director)

  2. Division of Radiation Physics, George Washington University Medical Center, 901 Twenty-Third Street, N.W. Washington DC, 20037, USA

    David J. Goodenough Ph.D. (Director) (Director)

  3. Department of the Army, Washington DC, 20310, USA

    Harold F. Davidson M.S. (Consultant, Office of the Director of Army Research) (Consultant, Office of the Director of Army Research)

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© 1983 Martinus Nijhoff Publishers, The Hague

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Malmud, L.S. (1983). Clinical Studies of the Abdomen: Scintigraphic and Other Techniques in the Management of Patients with Abdominal Disease. In: Reba, R.C., Goodenough, D.J., Davidson, H.F. (eds) Diagnostic Imaging in Medicine. NATO ASI Series, vol 61. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-6810-3_24

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  • DOI: https://doi.org/10.1007/978-94-009-6810-3_24

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