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Structure-Activity Relationships among Antitumour Quinones

  • J. S. Driscoll
Chapter
Part of the Developments in Pharmacology book series (DIPH, volume 3)

Abstract

The quinone function appears with considerable frequency among compounds which demonstrate clinical and pre-clinical antitumor activity. Sources of these compounds include fermentation products, synthetic materials and plant products. Familiar names among antitumor quinones include daunorubicin, adriamycin, mitomycin C, streptonigrin, lapachol, trenimon and carbazilquinone. New quinoid compounds currently under investigation by the National Cancer Institute (NCI) in the United States are AZQ, dihydroxyanthracenedione, aclacinomycin A and 7-OMEN.

Keywords

P388 Leukemia Dihydroxybenzene Isomer Quinoid Compound Jules Bordet Institute Substancial P388 Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Martinus Nijhoff Publishers, The Hague, Boston, London 1983

Authors and Affiliations

  • J. S. Driscoll

There are no affiliations available

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