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Nuclear imaging in clinical cardiology pp 173–217Cite as

Review of methods for computer analysis of global and regional left ventricular function from equilibrium gated blood pool scintigrams

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Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 32))

Abstract

Assuming a homogeneous distribution of the radioactive tracer (technetium-99m) in the blood pool, the changes in precordial count rates reflect the cyclic volume changes of the heart cavities. In the mid sixties Hoffmann and Kleine introduced heart studies with a single probe detector system and an ECG gating procedure to measure activity changes during the heart cycle [1]. However, this technique did not allow to differentiate between the left and right ventricles. To solve this problem, Adam et al. applied a few years later the gating procedure to a gamma camera and a computer system [2, 3]. To measure and visualize the cyclic changes in geometry and volume of the heart chambers, the data need to be collected over several hundreds of heart cycles. This results in a representative cardiac cycle divided into a number of time segments; the scintigraphic data are stored in computer memory in a corresponding number of frames. Modern computer systems allow the frames to be displayed on a video monitor screen in a closed loop movie format, thus allowing the detection of wall motion abnormalities. Gated equilibrium radionuclide ventriculography with technetium-99m as the radioactive tracer is nowadays a routinely applied noninvasive procedure for the assessment of left ventricular function at rest, stress and different stages of interventions [4].

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  1. Johan H. C. Reiber
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  1. Thoraxcenter Academic Hospital Dijkzigt, Erasmus University, Rotterdam, The Netherlands

    M. L. Simoons MD  & J. H. C. Reiber PhD  & 

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Reiber, J.H.C. (1984). Review of methods for computer analysis of global and regional left ventricular function from equilibrium gated blood pool scintigrams. In: Simoons, M.L., Reiber, J.H.C. (eds) Nuclear imaging in clinical cardiology. Developments in Cardiovascular Medicine, vol 32. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-6744-1_9

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