Skip to main content
SpringerLink
Log in

Drug bioavailability in the developing ruminant

  • Chapter
Veterinary Pharmacology and Toxicology

Abstract

Respiratory and gastrointestinal infections as well as systemic infections are common in newborn and developing animals. In fact, immunodeficiency makes the young animal more susceptible to disease, so there is often a need for drug administration in the newborn and the young animal. Antibiotics and chemotherapeutics will often have to be given.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 139.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 179.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Asai, T. (1973). Jpn. J. Vet. Sci., 35, 239–52

    Article  CAS  Google Scholar 

  2. de Backer, P., Belpaire, F. M., Debackere, M. et al. (1981). Zbl. Vet. Med. A., 28, 468–74

    Google Scholar 

  3. de Backer, P., Belpaire, F. M., Bogaert, M. G. et al. (1982). Am. J. Vet. Res., 43, 174–5

    Google Scholar 

  4. de Backer, P., Debackere, M. and de Corte-Baeten, K. (1978). J. Vet. Pharmacol. Ther., 1, 135–40

    Article  Google Scholar 

  5. de Backer, P. and Debackere, M. (1979). J. Vet. Pharmacol. Ther., 2, 195–202

    Article  Google Scholar 

  6. Barcroft, J., McAnally, R. A. and Phillipson, A. T. (1944). J. Exp. Biol., 20, 132–3

    CAS  Google Scholar 

  7. Bourne, D. W. A., Bevill, R. F. and Sharma, R. H. (1977). Am. J. Vet. Res., 38, 967–72

    CAS  PubMed  Google Scholar 

  8. Colin, G. (1886). Traité de Physiologie Comparée des Animaux. Vol. 2, p. 102. ( Paris: Bailliere )

    Google Scholar 

  9. de Corte-Baeten, K. and Debackere, M. (1975). Zbl. Vet. Med., 22, 704–12

    Google Scholar 

  10. Davis, L. E. (1979). J. Am. Vet. Med. Assoc., 246–7

    Google Scholar 

  11. Davis, L. E., Neff, C. A., Baggot, J. D. et al. (1972). Am. J. Vet. Res., 33, 2259–66

    CAS  PubMed  Google Scholar 

  12. Dobson, A. (1967). Fed. Proc., 26, 994–1000

    CAS  PubMed  Google Scholar 

  13. Dobson, A. and Phillipson, A. T. (1956). J. Physiol., 133, 76

    Google Scholar 

  14. Dobson, A. and Phillipson, A. T. (1968). In Handbook of Physiology, pp. 2761–74. ( Baltimore: Williams & Wilkins )

    Google Scholar 

  15. English, P. B. and Withy, D. (1959). Austr. Vet. J., 35, 187–93

    Article  CAS  Google Scholar 

  16. Flatt, W. P., Warner, R. G. and Loosli, J. K. (1959). Memoir 361, Agricultural experiment station, Cornell University

    Google Scholar 

  17. Hayashi, M., Bourne, D. W. A., Bevill, R. F. et al. (1979). Am. J. Vet. Res., 40, 1578–82

    CAS  PubMed  Google Scholar 

  18. Hill, K. J. (1968). Abomasal function. In Handbook of Physiology, p. 2747. ( Baltimore: Williams and Wilkins )

    Google Scholar 

  19. Huang, N. N. and High, R. H. (1953). J. Pediat., 42, 657–68

    Article  CAS  PubMed  Google Scholar 

  20. Huffman, E. M., Clark, C. H., Olson, J. D. et al. (1981). J. Vet. Pharmacol. Ther., 4, 225–31

    Article  CAS  PubMed  Google Scholar 

  21. Jaffe, S. J. and Danish, M. (1978). Drug Metab. Rev., 8, 303–18

    Article  Google Scholar 

  22. Jaffe, S. J. and Juchau, M. R. (1974). Ann. Rev. Pharmacol., 14, 219–38

    Article  Google Scholar 

  23. Juhasz, B., Szegedi, B. and Keresztes, M. (1976). Acta Vet. Acad. Sci. Hung., 26, 281–95

    CAS  PubMed  Google Scholar 

  24. Lapka, R., Urbanova, Z., Kobrylka, B. et al. (1978). Drug Metab. Disp., 6, 637–39

    CAS  Google Scholar 

  25. Lauwers, H. (1973). Morfologische bijdrage tot de kennis van het resorberend vermogen van rundervoormagen. Aggregaatsthesis, Rijks Universiteit Gent

    Google Scholar 

  26. Leat, W. M. F. (1970). In Phillipson, A. T. (ed.) Physiology of Digestion and Metabolism in the Ruminant, pp. 211–22. ( Newcastle-upon-Tyne: Oriel Press )

    Google Scholar 

  27. McGilliard, A. D. and Jacobson, N. L. (1965). In Dougherty, R. W. (ed.) Physiology of Digestion in the Ruminant. ( London: Butterworth )

    Google Scholar 

  28. Morselli, P. L. (1976). Drug Disposition during Development. ( New York: Spectrum Publications INC )

    Google Scholar 

  29. Morselli, P. L., Franco-Morselli, R. and Bossi, L. (1980). Clin. Pharmacokinetics, 5, 485–527

    Article  CAS  Google Scholar 

  30. Morselli, P. L. and Olive, G. (1978). Drug Measurement and Drug Effects in Laboratory Health Science. ( Basel: Karger )

    Google Scholar 

  31. Nielsen, P., Romvary, A. and Rasmussen, F. (1978). J. Vet. Pharmacol. Ther., 1, 37–46

    Article  CAS  Google Scholar 

  32. Nimmo, W. S. (1981). In Presscott, and Nimmo, W. S. (eds.) Drug Absorption, pp. 11–20. ( Lancaster: MTP Press )

    Google Scholar 

  33. Oyaert, W., Quin, J. I. and Clark, R. (1951). Onderstepoort J. Vet. Res., 25, 59

    CAS  Google Scholar 

  34. Righter, H. F., Showalter, D. H. and Teske, R. H. (1979). J. Vet. Pharmacol. Ther., 2, 203–8

    Article  Google Scholar 

  35. Sechserova, M., Sechser, T., Raskova, H. et al. (1979). Arzneim-Forsch./Drug. Res., 29, 650–1

    CAS  Google Scholar 

  36. Sechserova, M., Sechser, T., Raskova, H. et al. (1979). Arzneim-Forsch./Drug Res., 29, 804–7

    CAS  Google Scholar 

  37. Silverio, J. and Poole, J. W. (1973). Pediatrics, 51, 578–80

    CAS  PubMed  Google Scholar 

  38. Stevenson, I. H., Salem, S. A. M., O’Malley, K., et al. (1981). Drug Absorption, pp. 253–61. ( Lancaster: MTP Press )

    Google Scholar 

  39. Tamate, H. (1957). Tohoku J. Agric. Res., 8, 65

    Google Scholar 

  40. Tamate, H., McGilliard, A. D., Jacobson, N. L. et al. (1962). J. Dairy Sci., 45, 408

    Article  Google Scholar 

  41. Theodorides, V. J., Di Cuollo, C. J., Guarini, J. R. et al. (1968). Am. J. Vet. Res., 29, 643–5

    CAS  PubMed  Google Scholar 

  42. Thompson, S. M. R. and Black, W. D. (1978). Can. J. Comp. Med., 42, 255–9

    CAS  PubMed  Google Scholar 

  43. Trautmann, A. (1932). Arch. Tierernahr. Tierz., 7, 400

    Google Scholar 

  44. Wardrop, I. D. and Coombe, J. B. (1960). J. Agric. Sci. Camb., 54, 140

    Article  Google Scholar 

  45. Wardrop, I. D. and Coombe, J. B. (1961). Aust. J. Agric. Res., 12, 661

    Article  CAS  Google Scholar 

  46. Watson, A. D. J. (1974). Res. Vet. Sci., 16, 147–51

    CAS  PubMed  Google Scholar 

  47. Wilkinson, P. J. (1982). J. Antimicrob. Chemother., 9, 21–9

    Article  PubMed  Google Scholar 

  48. Wooley, J. L., Sigel, C. W. and Wels, C. M. (1980). Life Sci., 27, 1819–26

    Article  Google Scholar 

  49. Woolley, J. L. and Sigel, C. W. (1982). Am. J. Vet. Res., 43, 768–74

    CAS  PubMed  Google Scholar 

  50. Ziv, G., Nouws, J. F. M. and van Ginneken, C. A. M. (1982). J. Vet. Pharmacol. Ther., 5, 45–58

    Article  CAS  PubMed  Google Scholar 

  51. Ziv, G., Nouws, J. F. M., Groothuis, D. G. et al. (1977). Am. J. Vet. Res., 38, 1007–13

    CAS  PubMed  Google Scholar 

  52. Ziv, G., Wanner, M. and Nicolet, J. (1980). J. Vet. Pharmacol. Ther., 3, 87–94

    Article  CAS  Google Scholar 

Download references

Authors
  1. P. de Backer
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. G. Bogaert
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Ecole Nationale Vétérinaire, 23, chemin des Capelles, 31076, Toulouse Cédex, France

    Yves Ruckebusch

  2. Pharmacologie-Toxicologie, INRA, 180, chemin de Tournefeuille, 31300, Toulouse, France

    Pierre-Louis Toutain

  3. College of Veterinary Medicine, University of Illinois, 61801, Urbana, Illinois, USA

    Gary D. Koritz

Rights and permissions

Reprints and permissions

Copyright information

© 1983 MTP Press Limited

About this chapter

Cite this chapter

de Backer, P., Bogaert, M.G. (1983). Drug bioavailability in the developing ruminant. In: Ruckebusch, Y., Toutain, PL., Koritz, G.D. (eds) Veterinary Pharmacology and Toxicology. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-6604-8_13

Download citation

  • DOI: https://doi.org/10.1007/978-94-009-6604-8_13

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-6606-2

  • Online ISBN: 978-94-009-6604-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation