Axillary Lymph Nodes

  • Rosemary R. Millis
Part of the Current Histopathology book series (CUHI, volume 7)


The prognostic significance of axillary lymph node metastases in carcinoma of the breast is well known, and their presence or absence is the most important single prognostic indicator. As clinical assessment of axillary nodal status gives rise to about a 30% false positive and a 30% false negative rate, histological examination is essential for accurate evaluation.


Axillary Lymph Node Axillary Lymph Node Metastasis Metastatic Tumour Infiltrate Duct Carcinoma Sinus Histiocytosis 
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  1. 1.
    McDivitt, R. W. (1978). Breast carcinoma. Hum-Pathol., 9, 3–21PubMedCrossRefGoogle Scholar
  2. 2.
    Hutter, R. V.P. (1980). The influence of pathologic factors on breast cancer management. Cancer, 46, 961–976PubMedCrossRefGoogle Scholar
  3. 3.
    Sharkey, F. E. (1982). Biological meaning of stage and grade in hurgan breast cancer: review and hypothesis. Breast Cancer Res. Treat., 2, 299–322CrossRefGoogle Scholar
  4. 4.
    Nemoto, T., Vana, J., Bedwani, R.N., Baker, H.W., McGregor, F. H. and Murphy, G. P. (1980). Management and survival of breast cancer: results of a national survey by the American College of Surgeons. Cancer, 45, 2917–2924PubMedCrossRefGoogle Scholar
  5. 5.
    Rosen, P. P., Lesser, M. L., Kinne, D. W. and Beattie, E. J. (1983). Discontinuous or ‘skip’ metastases in breast carcinoma. Analysis of 1228 axillary dissections. Ann Surg., 197, 276–293PubMedCrossRefPubMedCentralGoogle Scholar
  6. 6.
    Fisher, E. R., Palekar, A., Rockette, H., Redmond, C. and Fisher, B. (1978). Pathologic findings from the National Surgical Adjuvant Breast Project (protocol No.4). V. Significance of axillary nodal micro and macrometastases. Cancer, 42, 2032–2038PubMedCrossRefGoogle Scholar
  7. 7.
    Rosen, P. P. Saigo, P.E., Braun, D.W., Weathers, E., Fracchia, A. A. and Kinne, D.W. (1981). Axillary micro- and macro-metastases in breast cancer. Ann. Surg., 194, 585–591PubMedCrossRefPubMedCentralGoogle Scholar
  8. 8.
    Mambo, N.C. and Gallager, H.S. (1977). Carcinoma of the breast. The prognostic significance of extranodal extension of axillary disease. Cancer, 39, 2280–2285PubMedCrossRefGoogle Scholar
  9. 9.
    Hartveit, F., Skjaerven, R. and Maehle, B.O. (1983). Prognosis in breast cancer patients with tumour cells in the efferent vessels of their axillary nodes. J. Pathol., 139, 379–382PubMedCrossRefGoogle Scholar
  10. 10.
    Johnson, W. T. and Helwig, E. B. (1969). Benign nevus cells in the capsule of lymph nodes. Cancer, 23, 747–753PubMedCrossRefGoogle Scholar
  11. 11.
    Ridolfi, R.L., Rosen, P.P. and Thaler, H (1977). Nevus cell aggregates associated with lymph nodes: estimated frequency and clinical significance. Cancer, 39, 164–171PubMedCrossRefGoogle Scholar
  12. 12.
    Erlandson, R. A. and Rosen, P. P. (1982) Electron microscopy of a nevus cell aggregate associated with an axillary lymph node. Cancer, 49, 269–272PubMedCrossRefGoogle Scholar
  13. 13.
    Turner, D. R. and Millis, R. R. (1980). Breast tissue inclusions in axillary lymph nodes. Histopathology, 4, 631–636PubMedCrossRefGoogle Scholar
  14. 14.
    Walker, A.N. and Fechner, R.E. (1982). Papillary carcinoma arising from ectopic breast tissue in an axillary lymph node. Diagnost. Gynecol. Obstet., 4, 141–145Google Scholar
  15. 15.
    Davies, J.D. and We¿b, A.J. (1982). Segmental lymph-node infarction after fine-needle aspiration. J. din. Pathol., 35, 855–857CrossRefGoogle Scholar
  16. 16.
    Egan, R. L and McSweeney, M. B. (1983). Intramammary lymph nodes. Cancer, 51, 1838–1842PubMedCrossRefGoogle Scholar

Copyright information

© Rosemary R. Millis 1984

Authors and Affiliations

  • Rosemary R. Millis
    • 1
  1. 1.Guy’s Hospital and Imperial Cancer Research Fund Breast Cancer Unit at Guy’s and New Cross HospitalsLondonUK

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