Abstract
In order to counteract potential DNA damage, organisms have evolved mechanisms to reverse, remove or tolerate such adverse influences. A distinction is made between ‘constitutive’ mechanisms, active at all times and ‘inducible’ ones that represent response to damage. The authors explore in this paper the extent to which low doses of clastogens can protect the system against higher doses. They show that one alkylating agent may substitute for another but that conditioning to induce protective effects is prevented by inhibition of protein synthesis.
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Rieger, R., Michaelis, A., Nicoloff, H. (1984). Pretreatment of Vicia Faba Root Tip Meristems with Low Clastogen Doses Protects against Aberration Induction by Subsequent Treatments: Induction of Repair Processes?. In: Chapman, G.P., Tarawali, S.A. (eds) Systems for Cytogenetic Analysis in Vicia Faba L.. Advances in Agricultural Biotechnology, vol 11. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-6210-1_4
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DOI: https://doi.org/10.1007/978-94-009-6210-1_4
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