Abstract
The initiation of an infection by bacteria and the subsequent development of the pathology is a very complex process. For simplicity, three aspects will be considered: i) attachment ii) resistance to host factors and iii) toxicity. All of these aspects of the problem can be investigated in cell culture. The study of attachment depends on the development of suitable epithelial cell lines. Resistance to host factors is limited by the availability of professional phagocytic cell lines. Toxins and toxicity of many types of bacteria have been examined in cell culture.
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© 1984 Martinus Nijhoff Publishers, Dordrecht
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Giugliano, L.G., Barer, M., Mann, G.F., Drasar, B.S. (1984). Tissue Culture Systems for the Examination of Bacterial Virulence. In: Hill, M.J. (eds) Models of Anaerobic Infection. New Perspectives in Clinical Microbiology, vol 10. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-6054-1_17
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DOI: https://doi.org/10.1007/978-94-009-6054-1_17
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-009-6056-5
Online ISBN: 978-94-009-6054-1
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