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Minimal Residual Disease in Acute Leukemia pp 293–310Cite as

Factors Associated with Relapse Following Allogeneic Bone Marrow Transplantation for Acute Leukemia in Remission

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Part of the book series: Developments in Oncology ((DION,volume 19))

Abstract

Although the advances in the treatment of patients with acute nonlymphoblastic leukemia (ANL) obtained with combination chemotherapy and supportive care are promising, the overall long-term leukemia-free survival and possible cure rates of the majority of these patients is poor (1).

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References

  1. Lister TA, Rohatiner AZS. 1982. The treatment of acute myelogenous leukemia in adults. Seminars in Hematology 19: 172–192.

    PubMed  CAS  Google Scholar 

  2. Preisler HD. 1982. Therapy for patients with acute myelocytic leukemia who enter remission: bone marrow transplantation or chemotherapy? Cancer Treatment Reports 66: 1467–1473.

    PubMed  CAS  Google Scholar 

  3. Miller DR, Leikin S, Albo V. 1981. Intensive therapy and prognostic factors in acute lymphoblastic leukaemia in childhood CCG 141. Modern Trends in Human Leukaemia IV. (ed. by R. Neth, R.C. Gallo, T. Graf, K. Mannweiler and K. Winkler), pp. 76–88, Springer Verlag, Berlin.

    Google Scholar 

  4. Henze G, Langermann HG, Ritter J, et al. 1981. Treatment strategy for different risk groups in childhood acute lymphoblastic leukaemia. A report from the BFM Study Group. Modern Trends in Human Leukaemia IV. (ed. by R. Neth, R.C. Gallo, T. Graf, K. Mannweiler and K. Winkler), pp. 87–93, Springer Verlag, Berlin.

    Chapter  Google Scholar 

  5. Haghbin M, Murphy ML, Tan CTC, et al. 1981. Intensive chemo therapy in children with acute lymphoblastic leukaemia (protocol). Cancer 33: 1491–1498.

    Article  Google Scholar 

  6. Chessells JM, Cornbleet M. 1979. Combination chemotherapy for bone marrow relapse in childhood lymphoblastic leukaemia. Medical and Pediatric Oncology 6: 359–365.

    Article  PubMed  CAS  Google Scholar 

  7. Reaman GH, Ladisch S, Echelberger C, et al. 1980. Improved treatment results in the management of single and multiple relapses of acute lymphoblastic leukemia. Cancer 45: 3090–3094.

    Article  PubMed  CAS  Google Scholar 

  8. Baccarani M, Corbelli G, Amadori S, et al. 1982. Adolescent and adult acute lymphoblastic leukemia: prognostic features and outcome of therapy. A study of 293 patients. Blood 60: 677–684.

    PubMed  CAS  Google Scholar 

  9. Mathé G, Jammet H, Pendic B, et al. 1959. Transfusions et greffes de moelle osseuse homologue chez des humains irradiés a haute dose accidentellement. Rev Franc Etudes Clin Biol 4: 226–233.

    PubMed  Google Scholar 

  10. Thomas ED, Lochte HL Jr, Lu WC, et al. 1957. Intravenous infusion of bone marrow in patients receiving radiation and chemotherapy. New England Journal of Medicine 257: 491–496.

    Article  PubMed  CAS  Google Scholar 

  11. Thomas ED, Lochte HL Jr, Cannon JH, et al. 1959. Supralethal whole body irradiation and isologous marrow transplantation in man. Journal of Clinical Investigation 38: 1709–1716.

    Article  PubMed  CAS  Google Scholar 

  12. Weiden PL, Sullivan KM, Flournoy N, et al. 1981. Antileukemic effect of chronic graft-versus-host disease: contribution to improved survival after allogeneic bone marrow transplantation. New England Journal of Medicine 304: 1529–1533.

    Article  PubMed  CAS  Google Scholar 

  13. Thomas ED, Buckner CD, Banaji M, et al. 1977. One hundred patients with acute leukemia treated by chemotherapy, total body irradiation, and allogeneic marrow transplantation. Blood 49: 511–533.

    PubMed  CAS  Google Scholar 

  14. Tutschka PJ, Elfenbein GJ, Sensenbrenner LL, et al. 1980. Preparative regimens for marrow transplantation in acute leukemia and aplastic anemia — Baltimore experience. American Journal of Pediatric Hematology/Oncology 2: 363–370.

    Google Scholar 

  15. Dicke KA, Kanojia MD, Zander AR. 1983. Allogeneic bone marrow transplantation in hematologic disorders. Cancer Bulletin 35: 23–29.

    Google Scholar 

  16. Thomas ED, Buckner CD, Clift RA, et al. 1979. Marrow transplantation for acute nonlymphoblastic leukemia in first remission. New England Journal of Medicine 301: 597–599.

    Article  PubMed  CAS  Google Scholar 

  17. Blume KG, Beutler E, Bross KJ, et al. 1980. Bone-marrow ablation and allogeneic marrow transplantation in acute leukemia. New England Journal of Medicine 302: 1041–1046.

    Article  PubMed  CAS  Google Scholar 

  18. Forman SJ, Spruce WE, Farbstein MJ, et al. 1983. Bone marrow ablation followed by allogeneic marrow grafting during first complete remission of acute nonlymphoblastic leukemia. Blood 61: 439–442.

    PubMed  CAS  Google Scholar 

  19. Gale RP: Clinical trials of bone marrow transplantation in leukemia. In: Gale RP, Fox CF (eds.). Biology of bone marrow transplantation. Academic Press, New York, 1980, pp. 11–27.

    Google Scholar 

  20. Kersey JH, Ramsay NKC, Kim T, et al. 1982. Allogeneic bone marrow transplantation in acute nonlymphoblastic leukemia: a pilot study. Blood 60: 400–403.

    PubMed  CAS  Google Scholar 

  21. Mannoni P, Vernant JP, Rodet M, et al. 1980. Marrow transplantation for acute nonlymphoblastic leukemia in first remission. Blut 41: 220–225.

    Google Scholar 

  22. Morgenstern GR, Powles RL. 1981. Allogeneic bone marrow transplantation for acute myeloid leukemia in first remission. Haematology and Blood Transfusion 26: 139–142.

    Article  PubMed  CAS  Google Scholar 

  23. Powles RL, Clink HM, Bandini G, et al. 1980. The place of bone marrow transplantation in acute myelogenous leukemia. Lancet i: 1047–1050.

    Article  Google Scholar 

  24. Speck B, Gratwohl A, Nissen C, et al. 1981. Further experience with cyclosporin A in allogeneic bone marrow transplantation. Experimental Hematology 9 (suppl. 9): 124 (Abstract).

    Google Scholar 

  25. Thomas ED, Clift RA, Buckner CD. 1982. Marrow transplantation for patients with acute nonlymphoblastic leukemia who achieve a first remission. Cancer Treatment Reports 66: 1463–1466.

    PubMed  CAS  Google Scholar 

  26. Zwaan FE, Jansen J, Colpin GGD, Simonis RFA. 1982. Marrow grafting for acute leukemia during remission — results in 23 patients. Experimental Hematology 10 (suppl. 10): 87.

    Google Scholar 

  27. Appelbaum FR, Clift RA, Buckner CD, et al. 1983. Allogeneic bone marrow transplantation for acute nonlymphoblastic leukemia after first relapse. Blood 61: 949–953.

    PubMed  CAS  Google Scholar 

  28. Buckner CD, Clift RA, Thomas ED, et al. 1982. Allogeneic marrow transplantation for patients with acute non-lymphoblastic leukemia in second remission. Leukemia Research 6: 395–399.

    Article  PubMed  CAS  Google Scholar 

  29. Thomas ED, Sanders JE, Flournoy N, et al. 1979. Marrow transplantation for patients with acute lymphoblastic leukemia in remission. Blood 54: 468–476.

    PubMed  CAS  Google Scholar 

  30. Barrett AJ, Rendra JR, Lucas CF, et al. 1982. Bone marrow transplantation for acute lymphoblastic leukaemia. British Journal of Haematology 52: 181–188.

    Article  PubMed  CAS  Google Scholar 

  31. Elfenbein GJ, Brogaonkar DS, Bias WB, et al. 1978. Cytogenetic evidence for recurrence of acute myelogenous leukem after allogeneic bone marrow transplantation in donor hemato poietic cells. Blood 52: 627–636.

    PubMed  CAS  Google Scholar 

  32. Gossett TC, Gale RP, Fleischman H, et al. 1979. Immunoblast sarcoma in donor cells after bone-marrow transplantation. New England Journal of Medicine 300: 904–907.

    Article  PubMed  CAS  Google Scholar 

  33. Fialkow PJ, Thomas ED, Bryant JI, et al. 1971. Leukaemic transformation of engrafted human marrow cells in vivo. Lancet i: 251.

    Article  Google Scholar 

  34. Goh K, Klemperer MR. 1977. In vivo leukemic transformation: cytogenetic evidence of in vivo leukemic transformation of engrafted marrow cells. American Journal of Hematology 2: 283–290.

    Article  PubMed  CAS  Google Scholar 

  35. Newburger PE, Latt SA, Pesando JM, et al. 1981. Leukemia relapse in donor cells after allogeneic bone-marrow transplantation. New England Journal of Medicine 304: 712–714.

    Article  PubMed  CAS  Google Scholar 

  36. Schubach WH, Hackman R, Neiman PE, et al. 1982. A monoclona immunoblastic sarcoma in donor cells bearing Epstein-Barr virus genomes following allogeneic marrow grafting for acutolymphoblastic leukemia. Blood 60: 180–187.

    PubMed  CAS  Google Scholar 

  37. Thomas ED, Bryant JI, Buckner CD, et al. 1972. Leukaemic transformation of engrafted human marrow cells in vivo. Lancet i: 1310–1313.

    Article  Google Scholar 

  38. Boyd CN, Ramberg RC, Thomas ED. 1982. The incidence of recurrence of leukemia in donor cells after allogeneic bone marrow transplantation. Leukemia Research 6: 833–837.

    Article  PubMed  CAS  Google Scholar 

  39. Zwaan FE, Hermans J. 1983. Report of the E.B.M.T. — Leukaemi Working Party. Experimental Hematology 11 (suppl. 13): 3–6.

    Google Scholar 

  40. ACS/NIH Bone Marrow Transplantation Report. 1975. Experimen Hematology 3: 149–155.

    Google Scholar 

  41. Hull CH, Nie NH. 1981. SPSS — update 7–9. Mac Graw Hill, New York.

    Google Scholar 

  42. Dixon WJ, Brown MB, Engelman L, et al. 1981. BMDP — statistical software 1981. University of California Press, Berkeley.

    Google Scholar 

  43. Harrison DT, Flournoy N, Ramberg R, et al. 1978. Relapse following marrow transplantation for acute leukemia. America Journal of Hematology 5: 191–202.

    Article  CAS  Google Scholar 

  44. Deeg HJ, Storb R, Thomas ED, et al. 1983. Marrow transplant ation for acute nonlymphoblastic leukemia in first remissio preliminary results of a randomized trial comparing cyclosporine and methotrexate for the prophylaxis of graft-versu host disease. Transplantation Proceedings 15: 1385–1388.

    Google Scholar 

  45. Denham S, Attridge S, Barfoot RK, Alexander P. 1983. Effect of cyclosporin A on the anti-leukaemia action associated with graft-versus-host disease. British Journal of Cancer 47: 791–795.

    Article  PubMed  CAS  Google Scholar 

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Authors
  1. F. E. Zwaan
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  2. J. Hermans
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Editors and Affiliations

  1. The Dr Daniël den Hoed Cancer Center, Rotterdam Radio-Therapeutic Institute, Rotterdam, The Netherlands

    B. Löwenberg MD, PhD  & A. Hagenbeek MD, PhD  & 

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© 1984 Springer Science+Business Media Dordrecht

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Zwaan, F.E., Hermans, J. (1984). Factors Associated with Relapse Following Allogeneic Bone Marrow Transplantation for Acute Leukemia in Remission. In: Löwenberg, B., Hagenbeek, A. (eds) Minimal Residual Disease in Acute Leukemia. Developments in Oncology, vol 19. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5670-4_23

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  • DOI: https://doi.org/10.1007/978-94-009-5670-4_23

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-9002-5

  • Online ISBN: 978-94-009-5670-4

  • eBook Packages: Springer Book Archive

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