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Calcium Antagonists and Anesthesia

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Part of the book series: Developments in Critical Care Medicine and Anesthesiolgy ((DCCA,volume 6))

Abstract

The purpose of this report is to update a previous, more detailed review of calcium entry blockers and the implications these drugs have on anesthesia practice.1 In our previous paper we did not include diltiazem which has recently been released and whose pharmacology has been reviewed by McAuley and Schroeder.2 A number of other excellent review articles pertinent to the subject have also appeared since our listing of pertinent papers.3–11

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Reference

  1. Reves JG, Kissin I, Lell WA, Tosone S: Calcium entry blockers: Uses and implications for the anesthesiologists. Anesthesiology 57:504–518, 1982

    Article  PubMed  CAS  Google Scholar 

  2. McAuley BJ, Schroeder JS: The use of diltiazem hydrochloride in cardiovascular disorders. Pharmacotherapy 2:121–133, 1982

    PubMed  CAS  Google Scholar 

  3. Braunwald E: Mechanism of action of calcium-channel-blocking agents. N Engl J Med 307:1618–1627, 1982

    Article  PubMed  CAS  Google Scholar 

  4. Movsesian MA: Calcium physiology in smooth muscle. Prog Cardiovasc Dis 25:211–224, 1982

    Article  PubMed  CAS  Google Scholar 

  5. White BC, Winegar CD, Wilson RF, Hoehner PJ, Trombley JH Jr: Possible role of calcium blockers in cerebral resuscitation: A review of the literature and synthesis for future studies. Crit Care Med 11:202–207, 1983

    Article  PubMed  CAS  Google Scholar 

  6. Weiss GB: New Perspectives on Calcium Antagonists. Bethesda, American Physiological Society, 1981

    Google Scholar 

  7. McAllister RG Jr: Clinical pharmacokinetics of calcium channel antagonists. J Cardiovasc Pharmacol 4:S340–S345, 1982

    Article  PubMed  Google Scholar 

  8. Covinsky JO, Hamburger SC: Slow channel blockers. South Med J 76:55–64, 1983

    Article  PubMed  CAS  Google Scholar 

  9. Fleckenstein A: History of calcium antagonists. Circ Res 52(Part II):I–3–I–17, 1983

    Google Scholar 

  10. Triggle DJ, Swamy VC: Calcium antagonists: Some chemical-pharmacologic aspects. Circ Res 52(Part II):I–17–I–28, 1983

    Google Scholar 

  11. Klein W, Brandt D, Vrecko K, Harringer M: Role of calcium antagonists in the treatment of essential hypertension. Circ Res 52(Part II):I–174–I–181, 1983

    Google Scholar 

  12. Braunwald E: Introduction: Calcium channel blockers. Am J Cardiol 46:1045–1046, 1980

    Article  PubMed  CAS  Google Scholar 

  13. Zimpfer M, Fitzal S, Tonczar L: Verapamil as a hypotensive agent during neuroleptanaesthesia. Br J Anaesth 53:885–889, 1981

    Article  PubMed  CAS  Google Scholar 

  14. Kates RA, Kaplan JA, McKeown PP, Freniere S: The cardiovascular effects of verapamil administration during coronary artery bypass graft surgery. Anesthesiology 57:A1, 1982

    Article  Google Scholar 

  15. Kopman EA: Intravenous verapamil to relieve pulmonary congestion in patients with mitral valve disease. Anesthesiology 58:374–376, 1983

    Article  PubMed  CAS  Google Scholar 

  16. Zaggy AP, Kates RA, Norfleet EA, Mueller RA, Heath KR: The comparative cardiovascular effects of verapamil, nifedipine, and diltiazem during halothane anesthesia. SCA Fifth Annual Meeting, San Diego, CA, April 1983, pp 95-96

    Google Scholar 

  17. Komai H, Rusy BF: Effect of halothane on rested-state and potentiated-state contractions in rabbit papillary muscle: Relationship to negative inotropic action. Anesth Analg 61:403–409, 1982

    Article  PubMed  CAS  Google Scholar 

  18. Blanck TJ, Thompson M: Calcium transport by cardiac sarcoplasmic reticulum: Modulation of halothane action by substrate concentration and pH. Anesth Analg 60:390–394, 1981

    PubMed  CAS  Google Scholar 

  19. Lynch C, Vogel S, Sperelakis N: Halothane depresses cardiac slow action potentials. Anesthesiology 49:407–413, 1978

    Article  Google Scholar 

  20. Altura BM, Altura BT, Carella A, et al: Vascular smooth muscle and general anesthetics. Fed Proc 39:1584–1591, 1980

    PubMed  CAS  Google Scholar 

  21. Tosone SR, Reves JG, Kissin I, Smith LR, Fournier SE: Hemodynamic responses to nifedipine in halothane anesthetized dogs. Anesth Analg 62: 000–000, 1983 (in press)

    Article  CAS  Google Scholar 

  22. Springman SR, Redon D, Rusy BF: The effect of nifedipine on the circulation during morphine N2O and halothane anesthesia in dogs. Anesth Analg 62:284–285, 1983

    Google Scholar 

  23. Kapur PA, Flacke WE: Epinephrine-induced arrhythmias and cardiovascular function after verapamil during halothane anesthesia in the dog. Anesthesiology 55:218–225, 1981

    Article  PubMed  CAS  Google Scholar 

  24. Norfleet EA, Heath KR, Kopp VJ, Sprague DH, Corke BC: Verapamil — different cardiovascular responses during N2O analgesia and halothane anesthesia. Anesthesiology 57:A75, 1982

    Article  Google Scholar 

  25. Hantler CB, Clifford BD, Kroll DA, Knight PR: Verapamil does have prolonged interactions with halothane. Anesthesiology 57:A2, 1982

    Article  Google Scholar 

  26. Kapur PA, Flacke WE: Lack of correlation of verapamil plasma level with cumulative protective effects against halothane — epinephrine ventricular arrhythmias. J Cardiovasc Pharmacol 4:652–657, 1982

    Article  PubMed  CAS  Google Scholar 

  27. Lawson NW, Kraynack BJ, Gintautas J: Neuromuscular and electrocardiographic responses to verapamil in dogs. Anesth Analg 62:50–54, 1983

    PubMed  CAS  Google Scholar 

  28. Schick EC Jr, Liang C, Heupler FA Jr, et al: Randomized withdrawal from nifedipine: Placebo-controlled study in patients with coronary artery spasm. Am Heart J 104:690–697, 1982

    Article  PubMed  Google Scholar 

  29. Freis ES, Lappas DG: Chronic administration of calcium entry blockers and the cardiovascular responses to high doses of fentanyl in man. Anesthesiology 57:A295, 1982

    Article  Google Scholar 

  30. Physicians’ Desk Reference, 37th Edition. Oradell, Medical Economics Company Inc., 1983, p 1580

    Google Scholar 

  31. Reves JG, Barker S, Smith LR: Significance of nifedipine plasma levels and hemodynamic changes during anesthesia induction. (Abstract) Anesthesiology (in press)

    Google Scholar 

  32. Marshall AG, Kissin I, Reves JG, Bradley EL Jr, Blackstone EH: Interaction between negative inotropic effects of halothane and nifedipine in the isolated rat heart. J Cardiovasc Pharmacol (in press)

    Google Scholar 

  33. Bikhazi GB, Leung I, Foldes FF: Interaction of neuromuscular blocking agents with calcium channel blockers. Anesthesiology 57:A268, 1982

    Article  Google Scholar 

  34. Maze M, Mason DM: Verapamil decreases the MAC for halothane in dogs. Anesth Analg 62:274, 1983

    Google Scholar 

  35. Kraynack BJ, Lawson NW, Gintautas J: Verapamil reduces indirect muscle twitch amplitude and potentiates pancuronium in vitro. Anesthesiology 57:A265, 1982

    Article  Google Scholar 

  36. Durant NN, Nguyen N, Briscoe JR, Katz RL: Potentiation of pancuronium and succinylcholine by verapamil. Anesthesiology 57:A267, 1982

    Article  Google Scholar 

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© 1984 Martinus Nijhoff Publishers, Boston

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Reves, J.G. (1984). Calcium Antagonists and Anesthesia. In: Stanley, T.H., Petty, W.C. (eds) Anesthesia and the Cardiovascular System. Developments in Critical Care Medicine and Anesthesiolgy, vol 6. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5668-1_6

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  • DOI: https://doi.org/10.1007/978-94-009-5668-1_6

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-9001-8

  • Online ISBN: 978-94-009-5668-1

  • eBook Packages: Springer Book Archive

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