Dietary habits and cholelithiasis
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Evidence exists that dietary factors play a regulatory role in plasma lipid levels1, biliary lipid composition2–4 and bile acid kinetics5–7. Dietary habits of gallstone subjects have been compared with those of matched controls8–11. Studies from France8.9 showed a higher caloric intake in gallstone subjects than in controls; studies from Australia showed that caloric intake was similar10 in the two groups, or lower11 in gallstone than in control subjects. As far as concerns epidemiological studies, data on eating habits reported in the Framingham study12 failed to reveal an association between presence of clinically diagnosed cases of gallbladder disease and daily intake of fat, protein and cholesterol. This paper deals with the eating habits as recorded during an epidemiological survey aimed primarily at investigating the prevalence of gallstone disease in a free-living population.
KeywordsDietary Habit Gallstone Disease Gallbladder Disease Cholesterol Gallstone Biliary Colic
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- 7.Cummings, J. H., Wiggins, H. S., Jenkins, D. J. A., Houston, H., Jivraj, T., Drasar, B. S. and Hill, M. J., (1978). Influence of diets high and low in animal fat on bowel habit, gastrointestinal transit time, fecal microflora, bile acid and fat excretion. J. Clin. Invest., 61, 953–963PubMedCrossRefGoogle Scholar
- 11.Burnett, W. (1971). The epidemiology of gallstones. Tijdschrift voor Gastroenterologie, 14, 79–89Google Scholar
- 13.The Rome Group for the Epidemiology and Prevention of Cholelithiasis (GREPCO) (1984). Prevalence of gallstone disease in an Italian adult female population. Am. J. Epidemiol. (In press)Google Scholar