Abstract
The pylorus (or ‘gatekeeper’) is the thickened muscle at the most distal end of the antrum. Its anatomy varies from species to species, but in man it consists of a thickened ring of circular muscle which is easily palpable at operation, or visible at endoscopy and which surrounds a pyloric canal of about 0.6 cm long. This most distal pyloric ring must be distinguished from the 2.5 cm length of increased thickness muscle which forms the terminal antrum, (fig. 1) This nomenclature is important as there has been much confusion: the term pyloric ‘sphincter’ is best avoided as it implies certain physiological characteristics which are not true of the pylorus. The pylorus is closely linked to the terminal antrum arid duodenal cap, both anatomically and physiologically, and some writers refer to the antro-pyloroduodenal segment as a whole. But we shall see the pyloric ring can sometimes function independently of both the antrum and the duodenum.
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References
Johnson AG. The pylorus. In: Thomas PA, Mann CV (Eds). Alimentary Sphincters and their Disorders. London, Macmillan 1984.
Eyre-Brook I A, Smallwood RH, Linhardt GE, Johnson AG. Timing of pyloric closure in man. Studies with impedance electrodes. Dig Dis Sci 1983; 28: 1106–15.
Capper WM, Airth GR, Kilby JO. A test for pyloric regurgitation. Lancet 1966; 2: 621–3.
Flint FJ, Grech P. Pyloric regurgitation and gastric ulcer. Gut 1970; 11: 735–7.
Codking JB, Grech P. Pyloric reflux and the healing of gastric ulcer. Gut 1973; 14: 555–7.
DuPlesis DJ. Pathogenesis of gastric ulceration. Lancet 1965; 1: 974–8.
Black RB, Roberts G, Rhodes J. The effect of healing on bile reflux in gastric ulcer. Gut 1971; 12: 552–8.
Dewar P, King R, Johnston D (1983). Bile acid and lysolecithin concentrations in the stomach of patients with gastric ulcer: before and after treatment
Muller-Lissner SA, Fimmel CJ, Blum AL. Is there a relationship between duodenogastric reflux, gastric ulcer and gastritis? In: Akkermans LMA, Johnson AG, Read NW (Eds). Gastric and Gastroduodenal Motility. New York, Praeger 1984.
Johnson AG. Cholecystectomy and gallstone dyspepsia. Ann Roy Coll Surg Eng 1975; 56: 69–80.
Eyre-Brook IA, Holroyd AM, Johnson AG. A single isotope method of postprandial duodenogastric reflux assessment using 99mTc-labelled IDA in patients with gallstones. Clinical Physics and Physiological Measurement 1983; 4: 299–307.
Eyre-Brook IA, Smythe A, Bird NC, Mangnall YF, Johnson AG. Total bile acid and pancreatic phosphiliphase A2 concentrations in the stomach in patients with gastric ulcer kand gallbladder disease. Brit J Surg (Abstract). In press.
Miller LJ, Malagelada L-R, Lengstreth GF, Go VLW. Dysfunction of the stomach with gastric ulceration. Dig Dis Sci 1980; 25: 857–64.
Kelly KA, Code CF. Duodenal-gastric reflux and slowed gastric emptying by electrical pacing of the canine duodenal pacesetter potential. Gastroenterology 1977; 72: 429–33.
Johnson AG. Peptic ulcer and the pylorus. Lancet 1979; 1: 710–2.
Eyre-Brook IA, Read NW, Brownson T, Johnson AG. The influence of che- nodeoxycholic acid upon fasting antro-duodenal motility and reflux. Brit J Surg (Abstract). In press.
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© 1985 Martinus Nijhoff Publishers, Dordrecht
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Johnson, A.G. (1985). Pyloric function and its role in the pathogenesis of gastric ulcer. In: Nelis, G.F., Boevé, J., Misiewics, J.J. (eds) Peptic Ulcer Disease: Basic and Clinical Aspects. Developments in Gastroenterology, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5034-4_5
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DOI: https://doi.org/10.1007/978-94-009-5034-4_5
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