Abstract
Our objectives in examining murine liver adherent populations have been three-fold. Since the largest body of tissue macrophages are resident Kupffer cells, they seemed a prime target for application of newly available monoclonal and recombinant reagents in a rigorous characterization. Large gaps exist in our knowledge of the surface phenotype, biosynthetic capacity, activation state, and cytocidal potential of hepatic macrophages. Such questions acquire particular relevance when viewed in light of the specific targeting of certain pathogens (e.g., Leishmania donovani) to the liver.
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© 1985 Martinus Nijhoff Publishers, Dordrecht
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Lepay, D.A., Steinman, R.M., Nathan, C.F., Murray, H.W., Cohn, Z.A. (1985). Properties of resident and inflammatory macrophages in mouse liver. In: van Furth, R. (eds) Mononuclear Phagocytes. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5020-7_51
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DOI: https://doi.org/10.1007/978-94-009-5020-7_51
Publisher Name: Springer, Dordrecht
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