Flow Cytometry in Lymphoma/Leukemia Diagnosis

  • John W. Parker
Part of the Developments in Oncology book series (DION, volume 31)


As Robert Lukes’ first fellow at USC, in 1964, and his associate since then, it is a great pleasure to see him honored by this symposium. Much of what is being presented here has been influenced directly or indirectly by his ideas and concepts of the biology of lymphomas. His hypothesis of blocks in transformation as a mechanism for the development of follicular center cell lymphomas (Lukes and Collins) is now widely accepted. Parallel findings by other investigators make it now common to speak of impairment in differentiation (“frozen stages”) to explain the derivation of cells in hematopoietic neoplasms. 1,2 All of the answers are not in, but no matter what the final outcome, Dr. Lukes’ ideas and proposals have stimulated many investigators, pathologists and clinicians to change their thinking about lymphomas.


Chronic Lymphocytic Leukemia Angle Scatter Lineage Switch Acute Nonlymphocytic Leukemia Persistent Generalize Lymphadenopathy 
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© Martinus Nijhoff Publishers, Dordrecht 1985

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  • John W. Parker

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