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Future Aspects in Contraception pp 219–227Cite as

Gossypol—the male fertility-regulating agent

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Abstract

The discovery of the activity of gossypol as a male antifertility agent has aroused considerable interest among students of reproductive biology1, and constitutes a major lead in the search for methods of regulation of fertility in males. In 1957 the Chinese scientist Liu-Bao-Shu reported in a local medical journal of Shanghai that in places where crude cottonseed oil was consumed in cooking there were usually more cases of infertility2. It was only in early 1970 that a systematic study established that the active ingredient in cottonseed oil responsible for the induction of infertility is gossypol (C3OH30O8), a polyphenol.

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Authors
  1. N. R. Kalla
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Editors and Affiliations

  1. Division of Gynaecological Endocrinology, Department of Obstetrics and Gynaecology, University of Heidelberg, D-6900, Heidelberg 1, West Germany

    B. Runnebaum , T. Rabe  & Ludwig Kiesel ,  & 

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© 1985 MTP Press Limited

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Kalla, N.R. (1985). Gossypol—the male fertility-regulating agent. In: Runnebaum, B., Rabe, T., Kiesel, L. (eds) Future Aspects in Contraception. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4910-2_10

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  • DOI: https://doi.org/10.1007/978-94-009-4910-2_10

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-8675-2

  • Online ISBN: 978-94-009-4910-2

  • eBook Packages: Springer Book Archive

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