Abstract
Orally administered testosterone is almost ineffective because of its premature inactivation by the liver. Intramuscular administration and implantation are unfavourable for practical reasons. The fatty acid ester of the androgen, testosterone undecanoate (TU), has been shown to be an orally effective preparation, resulting in an increase1 of plasma T, a decrease of elevated gonadotropin concentrations1 and improvement in sexual behaviour2.
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References
Mies, R. and Krempl, S. (1980). Die Wirkung von Testosteronundecanoat beim männlichen Hypogonadismus. Med. Welt, 31, 619
Luisi, M. and Franchi, F. (1980). Double-blind group comparative study of testosterone undecanoate and Mesterolone in hypogonadal male patients. J. Endocrinol. Invest, 3, 305
Eliasson, R. (1981). Analysis of semen. In Burger, H. and de Kretser, D. (eds.). The Testis, p. 381. ( New York: Raven Press )
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da Rugna, D., Saastamoinen, J. (1984). Effects of testosterone undecanoate on semen quality and sexual behaviour. In: Thompson, W., Harrison, R.F., Bonnar, J. (eds) The Male Factor in Human Infertility Diagnosis and Treatment. Studies in Fertility and Sterility, vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4898-3_27
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DOI: https://doi.org/10.1007/978-94-009-4898-3_27
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-8669-1
Online ISBN: 978-94-009-4898-3
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